PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31163124-8	2019	PPARalpha antagonist (MK886), PPARbeta antagonist (GSK0660), and PPARgamma antagonist (GW9662) reversed the protection of bezafibrate in NRK-52E, and abrogated the up-regulation of CYP4A-20-HETE produced by bezafibrate.	Bezafibrate	122-133	peroxisome proliferator activated receptor delta	Homo sapiens	30-38	
15936983-3	2005	Indeed, treatment with the PPARalpha-PPARbeta/delta agonist bezafibrate led to the up-regulation of I-BABP mRNA levels in the human intestine-derived Caco-2 cells.	Bezafibrate	60-71	peroxisome proliferator activated receptor delta	Homo sapiens	37-45	
21484566-6	2011	PPAR-delta activators increase the capacity for fat oxidation in skeletal muscle.Clinical experience with bezafibrate, which activates PPAR-delta and -alpha, and studies on the PPAR-alpha/delta activator tetradecylthioacetic acid, the PPAR-delta activator GW501516, and combinations of the PPAR-alpha activator fenofibrate with rosiglitazone or pioglitazone have encouraged attempts to develop single molecules that activate two or all three PPARs.	Bezafibrate	106-117	peroxisome proliferator activated receptor delta	Homo sapiens	0-10	
21484566-6	2011	PPAR-delta activators increase the capacity for fat oxidation in skeletal muscle.Clinical experience with bezafibrate, which activates PPAR-delta and -alpha, and studies on the PPAR-alpha/delta activator tetradecylthioacetic acid, the PPAR-delta activator GW501516, and combinations of the PPAR-alpha activator fenofibrate with rosiglitazone or pioglitazone have encouraged attempts to develop single molecules that activate two or all three PPARs.	Bezafibrate	106-117	peroxisome proliferator activated receptor delta	Homo sapiens	135-145	
18356690-5	2008	While fenofibrate and LY518674 showed exclusive dependency on PPARalpha for these activities, bezafibrate and gemfibrozil exhibited dependency on PPARbeta/delta and PPARgamma as well.	Bezafibrate	94-105	peroxisome proliferator activated receptor delta	Homo sapiens	146-154	
22550474-4	2012	Expression of either functional or dominant negative hPPARdelta blocked bezafibrate-induced PPARalpha-dependent hepatomegaly and blocked the effect of bezafibrate on the transcription of PPARalpha target genes.	Bezafibrate	72-83	peroxisome proliferator activated receptor delta	Homo sapiens	53-63	
22550474-4	2012	Expression of either functional or dominant negative hPPARdelta blocked bezafibrate-induced PPARalpha-dependent hepatomegaly and blocked the effect of bezafibrate on the transcription of PPARalpha target genes.	Bezafibrate	151-162	peroxisome proliferator activated receptor delta	Homo sapiens	53-63