PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30553827-0	2019	A fungicide miconazole ameliorates tri-o-cresyl phosphate-induced demyelination through inhibition of ErbB/Akt pathway.	Miconazole	12-22	AKT serine/threonine kinase 1	Homo sapiens	107-110	
31109399-8	2019	The initial mechanism of MCZ-mediated cell death in human breast cancer MDA-MB-231 cells involves an increase in the Bax/Bcl-2 ratio, downregulation of apoptosis induced by Akt and p-Akt-473, a simultaneous upregulation of the receptor-interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) protein expression, and ROS production to induce necroptosis.	Miconazole	25-28	AKT serine/threonine kinase 1	Homo sapiens	173-176	
31109399-8	2019	The initial mechanism of MCZ-mediated cell death in human breast cancer MDA-MB-231 cells involves an increase in the Bax/Bcl-2 ratio, downregulation of apoptosis induced by Akt and p-Akt-473, a simultaneous upregulation of the receptor-interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) protein expression, and ROS production to induce necroptosis.	Miconazole	25-28	AKT serine/threonine kinase 1	Homo sapiens	183-186	
30553827-5	2019	Mechanistically, miconazole inhibited the TOCP-induced activation of ErbB/Akt signaling, and enhanced the myelin basic protein (MBP) expression.	Miconazole	17-27	AKT serine/threonine kinase 1	Homo sapiens	74-77	
30553827-6	2019	In a glial cell model sNF96.2 cells, miconazole restored the TOCP-inhibited MBP expression, and promoted cell differentiation as well as cell migration by inhibiting the activation of ErbB/Akt signaling pathway.	Miconazole	37-47	AKT serine/threonine kinase 1	Homo sapiens	189-192	
30553827-7	2019	In sum, miconazole, a synthetic imidazole fungicide, could ameliorate the symptoms and histopathological changes of OPIDN, probably by promoting glial cell differentiation and migration to enhance myelination via inhibiting the activation of ErbB/Akt.	Miconazole	8-18	AKT serine/threonine kinase 1	Homo sapiens	247-250