PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11282276-1 2000 The imidazole antifungal drugs econazole and miconazole have previously been shown to disrupt steroidogenesis in Leydig and adrenal cells by inhibiting 17alpha-hydroxylase/17,20-lyase (P450c17) enzyme activity, thus reducing the conversion of progesterone to androstenedione. Miconazole 45-55 cytochrome P450, family 17, subfamily a, polypeptide 1 Mus musculus 185-192