PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8555254-5	1996	Because of those data we hypothesized that increased hepatic cholesteryl ester mass and synthesis rates in rabbit liver cells are associated with an increase in ACAT mRNA14b levels.	Cholesterol Esters	61-78	sterol O-acyltransferase 1	Oryctolagus cuniculus	161-165	
3358947-0	1988	Influence of the acyl-CoA: cholesterol O-acyltransferase inhibitor, CL 277082, on cholesteryl ester accumulation in rabbit macrophage-rich granulomas and hepatic tissue.	Cholesterol Esters	82-99	sterol O-acyltransferase 1	Oryctolagus cuniculus	17-56	
3358947-1	1988	The influence of the acyl-CoA: cholesterol O-acyltransferase (ACAT) inhibitor, CL 277082, on macrophage cholesteryl ester accumulation in a rabbit carrageenan granuloma macrophage-foam cell model was studied.	Cholesterol Esters	104-121	sterol O-acyltransferase 1	Oryctolagus cuniculus	62-66	
3675707-4	1987	The enzymes acyl-CoA: cholesterol acyltransferase (ACAT), acid cholesteryl esterase (ACE) and neutral cholesteryl esterase (NCE) may play key roles in the accumulation of cholesteryl esters in the arterial wall.	Cholesterol Esters	171-189	sterol O-acyltransferase 1	Oryctolagus cuniculus	12-49	
3675707-4	1987	The enzymes acyl-CoA: cholesterol acyltransferase (ACAT), acid cholesteryl esterase (ACE) and neutral cholesteryl esterase (NCE) may play key roles in the accumulation of cholesteryl esters in the arterial wall.	Cholesterol Esters	171-189	sterol O-acyltransferase 1	Oryctolagus cuniculus	51-55	
11223434-7	2001	In the liver a decrease by atorvastatin in free cholesterol substrate for ACAT may amplify the effect of F 12511 on cholesteryl ester content leading to a diminution, in at least an additive manner, of the assembly and secretion of atherogenic lipoproteins in New Zealand rabbits which have developed an endogenous hypercholesterolemia.	Cholesterol Esters	116-133	sterol O-acyltransferase 1	Oryctolagus cuniculus	74-78	
10634802-1	2000	Given the significance of cholesteryl ester (CE) accumulation in macrophage foam cell formation, we hypothesized that inhibitors of acyl-CoA:cholesterol O-acyltransferase (ACAT) would produce a histologically stable lesion by limiting macrophage enrichment and thereby a source of matrix metalloproteinases (MMPs).	Cholesterol Esters	26-43	sterol O-acyltransferase 1	Oryctolagus cuniculus	132-170	
10634802-1	2000	Given the significance of cholesteryl ester (CE) accumulation in macrophage foam cell formation, we hypothesized that inhibitors of acyl-CoA:cholesterol O-acyltransferase (ACAT) would produce a histologically stable lesion by limiting macrophage enrichment and thereby a source of matrix metalloproteinases (MMPs).	Cholesterol Esters	26-43	sterol O-acyltransferase 1	Oryctolagus cuniculus	172-176	
8555254-8	1996	Treatment of parenchymal cells with CI-976, an ACAT inhibitor, showed a marked reduction in cholesteryl ester synthetic rate compared to beta VLDL controls but displayed no change in ACAT mRNA14b levels.	Cholesterol Esters	92-109	sterol O-acyltransferase 1	Oryctolagus cuniculus	47-51	
1854363-9	1991	The basal activity of ACAT in hepatic membranes was significantly lower in the resistant rabbits compared to normal rabbits (138 +/- 11 vs 268 +/- 19 pmol cholesteryl ester/min/mg in resistant and normal rabbits respectively); when fed a 0.25% cholesterol-enriched diet, the enzyme was induced 6-fold in normal animals but was increased only 2-fold in the resistant animal.	Cholesterol Esters	155-172	sterol O-acyltransferase 1	Oryctolagus cuniculus	22-26	
2297340-2	1990	Sterol synthesis was measured by the incorporation of 14C-acetate into sterol, and ACAT activity, by the incorporation of 14C-oleate into cholesteryl ester.	Cholesterol Esters	138-155	sterol O-acyltransferase 1	Oryctolagus cuniculus	83-87