PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1201380-4 1975 3 Both the tryptophan and histidine residues seemed to be essential for bombesin-like activity. Tryptophan 11-21 gastrin releasing peptide Homo sapiens 72-80 3801011-1 1986 The conformational flexibility of the tetradecapeptide hormone bombesin has been studied using circular dichroism and fluorescence of its single tryptophan residue. Tryptophan 145-155 gastrin releasing peptide Homo sapiens 63-71 3841693-4 1985 The data support the following prerequisites for the maximal neuromodulatory role of bombesin-like peptides on gastric secretion: Trp is required at position 8; Gln and His are important at positions 7 and 12, respectively; Leu replacement by Phe, which occurs in the litorin subfamily, modifies the response; and unspecified amino acids or sequences are also involved in the N-terminal region of bombesin-like peptides. Tryptophan 130-133 gastrin releasing peptide Homo sapiens 85-93 27665193-4 2017 The SERS results for BN and its fragment demonstrated that (1) three amino acids from these peptides sequence; i.e., l-histidine, l-methionine, and l-tryptophan, are involved in the interaction with gold coated silicon wafer and (2) the strength of these interactions depends upon the aforementioned amino acids position in the peptide sequence. Tryptophan 148-160 gastrin releasing peptide Homo sapiens 21-23 21882401-0 2004 3-Cyano-4-[(18)F]fluoro-benzoyl-Ala(SO3H)-Ala(SO3H)-Ava-Gln-Trp-Ala-Val-NMeGly-His-Sta-Leu-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids), which binds to the GRP receptor (GRPR) with high affinity and specificity (1). Tryptophan 60-63 gastrin releasing peptide Homo sapiens 109-117 23390665-3 2004 It shares an identical C-terminal region (-Trp-Ala-Val-Gly-His-Leu-Met-NH2) with gastrin-releasing peptide (GRP), which is responsible for receptor binding and signal transduction (4, 5). Tryptophan 43-46 gastrin releasing peptide Homo sapiens 81-106 23390665-3 2004 It shares an identical C-terminal region (-Trp-Ala-Val-Gly-His-Leu-Met-NH2) with gastrin-releasing peptide (GRP), which is responsible for receptor binding and signal transduction (4, 5). Tryptophan 43-46 gastrin releasing peptide Homo sapiens 108-111 22514805-0 2004 (99m)Tc-Labeled, PEGylated (N(alpha)His)Ac-beta(3)hLys-betaAla-betaAla-Gln(7)-Trp(8)-Ala(9)-Val(10)-Gly(11)-His(12)-Cha(13)-Nle(14)-NH2 The (99m)Tc-labeled, PEGylated (N(alpha)His)Ac-beta(3)hLys-betaAla-betaAla-Gln(7)-Trp(8)-Ala(9)-Val(10)-Gly(11)-His(12)-Cha(13)-Nle(14)-NH2 (Lys-BN), abbreviated as (99m)Tc-PEGx-Lys-BN (x = 5, 10, and 20 kDa), are PEGylated bombesin (BN) analogs that were synthesized by Dapp et al. Tryptophan 78-81 gastrin releasing peptide Homo sapiens 360-368 21882401-0 2004 3-Cyano-4-[(18)F]fluoro-benzoyl-Ala(SO3H)-Ala(SO3H)-Ava-Gln-Trp-Ala-Val-NMeGly-His-Sta-Leu-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids), which binds to the GRP receptor (GRPR) with high affinity and specificity (1). Tryptophan 60-63 gastrin releasing peptide Homo sapiens 181-206 21882401-0 2004 3-Cyano-4-[(18)F]fluoro-benzoyl-Ala(SO3H)-Ala(SO3H)-Ava-Gln-Trp-Ala-Val-NMeGly-His-Sta-Leu-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids), which binds to the GRP receptor (GRPR) with high affinity and specificity (1). Tryptophan 60-63 gastrin releasing peptide Homo sapiens 208-211 21882401-0 2004 3-Cyano-4-[(18)F]fluoro-benzoyl-Ala(SO3H)-Ala(SO3H)-Ava-Gln-Trp-Ala-Val-NMeGly-His-Sta-Leu-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids), which binds to the GRP receptor (GRPR) with high affinity and specificity (1). Tryptophan 60-63 gastrin releasing peptide Homo sapiens 262-265 20641703-0 2004 (64)Cu-1,4,7-Triazacyclononane-1,4-diacetate-8-aminooctanoic acid-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Tryptophan 70-73 gastrin releasing peptide Homo sapiens 116-124 20641535-0 2004 (111)In-DOTA-Gly-benzoyl-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1). Tryptophan 35-38 gastrin releasing peptide Homo sapiens 81-89 20641535-0 2004 (111)In-DOTA-Gly-benzoyl-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1). Tryptophan 35-38 gastrin releasing peptide Homo sapiens 153-178 20641535-0 2004 (111)In-DOTA-Gly-benzoyl-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1). Tryptophan 35-38 gastrin releasing peptide Homo sapiens 180-183 20641306-4 2004 GRP and BN share an identical C-terminal region (-Trp-Ala-Val-Gly-His-Leu-Met-NH2), which is necessary for receptor binding and signal transduction (5, 6). Tryptophan 50-53 gastrin releasing peptide Homo sapiens 0-3 20641903-4 2004 GRP and BN share an identical C-terminal region (-Trp-Ala-Val-Gly-His-Leu-Met-NH2), which is necessary for receptor binding and signal transduction (5, 6). Tryptophan 50-53 gastrin releasing peptide Homo sapiens 0-3 20641937-4 2004 GRP and BN share an identical C-terminal region (-Trp-Ala-Val-Gly-His-Leu-Met-NH2), which is necessary for receptor binding and signal transduction (5, 6). Tryptophan 50-53 gastrin releasing peptide Homo sapiens 0-3 20641508-4 2004 GRP and BN share an identical C-terminal region (-Trp-Ala-Val-Gly-His-Leu-Met-NH2) which is necessary for receptor binding and signal transduction (56). Tryptophan 50-53 gastrin releasing peptide Homo sapiens 0-3 20641703-0 2004 (64)Cu-1,4,7-Triazacyclononane-1,4-diacetate-8-aminooctanoic acid-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Tryptophan 70-73 gastrin releasing peptide Homo sapiens 188-213 20641703-0 2004 (64)Cu-1,4,7-Triazacyclononane-1,4-diacetate-8-aminooctanoic acid-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Tryptophan 70-73 gastrin releasing peptide Homo sapiens 215-218 20641895-0 2004 (64)Cu-1,4,7-Triazacyclononane-1,4-7-triacetic acid-8-aminooctanoic acid-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Tryptophan 77-80 gastrin releasing peptide Homo sapiens 123-131 20641895-0 2004 (64)Cu-1,4,7-Triazacyclononane-1,4-7-triacetic acid-8-aminooctanoic acid-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Tryptophan 77-80 gastrin releasing peptide Homo sapiens 195-220 20641895-0 2004 (64)Cu-1,4,7-Triazacyclononane-1,4-7-triacetic acid-8-aminooctanoic acid-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 The amphibian bombesin (BBN or BN, a peptide of 14 amino acids) is an analog of human gastrin-releasing peptide (GRP, a peptide of 27 amino acids) that binds to GRP receptors (GRPR) with high affinity and specificity (1, 2). Tryptophan 77-80 gastrin releasing peptide Homo sapiens 222-225 19243162-6 2009 In the NMR spectra of both the metallated and unmetallated AMBA ligand, a stacking interaction between the amino benzoyl residue in the linker and a tryptophan in the truncated bombesin [BBN(7-14)-NH(2)] peptide targeting group was found. Tryptophan 149-159 gastrin releasing peptide Homo sapiens 177-185 20641678-1 2004 Both GRP and BBN share an amidated C-terminus sequence homology of 7 amino acids, -Trp-Ala-Val-Gly-His-Leu-Met-NH2. Tryptophan 83-86 gastrin releasing peptide Homo sapiens 5-8 20641607-12 2004 (177)Lu-AMBA consists of two components: a peptide of eight amino acids that is composed of the seven common amino acids in the C-terminus of BBN/GRP (Trp-Ala-Val-Gly-His-Leu-Met) and a complex of (177)Lu-DOTA attached to the N-terminus of the peptide via a glycyl-4-aminobezoic acid linker. Tryptophan 151-154 gastrin releasing peptide Homo sapiens 142-149 20641369-3 2004 Both GRP and BN share an amidated C-terminus sequence homology of seven amino acids, -Trp-Ala-Val-Gly-His-Leu-Met-NH2. Tryptophan 86-89 gastrin releasing peptide Homo sapiens 5-8 20641835-2 2004 Both GRP and BN share an amidated C-terminus sequence homology of seven amino acids, -Trp-Ala-Val-Gly-His-Leu-Met-NH2. Tryptophan 86-89 gastrin releasing peptide Homo sapiens 5-8 20641503-3 2004 Both GRP and BN share an amidated C-terminus sequence homology of seven amino acids, -Trp-Ala-Val-Gly-His-Leu-Met-NH2. Tryptophan 86-89 gastrin releasing peptide Homo sapiens 5-8 20641773-2 2004 Both GRP and BN share an amidated C-terminus sequence homology of 7 amino acids, -Trp-Ala-Val-Gly-His-Leu-Met-NH2. Tryptophan 82-85 gastrin releasing peptide Homo sapiens 5-8 20641931-0 2004 (99m)Tc-pGlu-Gln-Trp-Ala-Val-Gly-His-Phe-Met-NH2 Bombesin (BBN or BN)-like peptide is an analog of human gastrin-releasing peptide (GRP) that binds to GRP receptors (GRP-R) (1). Tryptophan 17-20 gastrin releasing peptide Homo sapiens 49-57 20641931-0 2004 (99m)Tc-pGlu-Gln-Trp-Ala-Val-Gly-His-Phe-Met-NH2 Bombesin (BBN or BN)-like peptide is an analog of human gastrin-releasing peptide (GRP) that binds to GRP receptors (GRP-R) (1). Tryptophan 17-20 gastrin releasing peptide Homo sapiens 105-130 20641931-0 2004 (99m)Tc-pGlu-Gln-Trp-Ala-Val-Gly-His-Phe-Met-NH2 Bombesin (BBN or BN)-like peptide is an analog of human gastrin-releasing peptide (GRP) that binds to GRP receptors (GRP-R) (1). Tryptophan 17-20 gastrin releasing peptide Homo sapiens 132-135 20641605-3 2004 Both GRP and BN share an amidated C-terminus sequence homology of seven amino acids, -Trp-Ala-Val-Gly-His-Leu-Met-NH2. Tryptophan 86-89 gastrin releasing peptide Homo sapiens 5-8 11350598-1 2001 The formation of N-peptidyl-2-iminothiolanes with bombesin (BN) antagonist (D-Trp(6),Leu(13)-psi[CH(2)NH]-Phe(14))BN(6-14) and D-Trp-Gln-Trp-NH(2). Tryptophan 78-81 gastrin releasing peptide Homo sapiens 50-58 20641271-3 2004 Both GRP and BN share an amidated C-terminus sequence homology of 7 amino acids, -Trp-Ala-Val-Gly-His-Leu-Met-NH2. Tryptophan 82-85 gastrin releasing peptide Homo sapiens 5-8 20641296-2 2004 Both GRP and BN share an amidated C-terminus sequence homology of seven amino acids, -Trp-Ala-Val-Gly-His-Leu-Met-NH2. Tryptophan 86-89 gastrin releasing peptide Homo sapiens 5-8 12874010-7 2003 Re(I)-BBN conjugates were prepared by the reaction of [Re(Br)(3)(CO)(3)](2-) and Dpr-Ser-Ser-Ser-Gln-Trp-Ala-Val-Gly-His-Leu-Met-(NH(2)) with gentle heating. Tryptophan 101-104 gastrin releasing peptide Homo sapiens 6-9 11350598-1 2001 The formation of N-peptidyl-2-iminothiolanes with bombesin (BN) antagonist (D-Trp(6),Leu(13)-psi[CH(2)NH]-Phe(14))BN(6-14) and D-Trp-Gln-Trp-NH(2). Tryptophan 78-81 gastrin releasing peptide Homo sapiens 60-62 9548537-3 1998 This study involves the synthesis and initial evaluation of technetium diaminedithiolate analogues derived from the potent bombesin analogue Pyr-Gln-Lys-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 (Lys3-bombesin). Tryptophan 169-172 gastrin releasing peptide Homo sapiens 123-131 9548537-3 1998 This study involves the synthesis and initial evaluation of technetium diaminedithiolate analogues derived from the potent bombesin analogue Pyr-Gln-Lys-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 (Lys3-bombesin). Tryptophan 169-172 gastrin releasing peptide Homo sapiens 207-215 9266477-1 1997 The structure of neuromedin C, a 10-residue bombesin-like neuropeptide with the sequence Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2, has been investigated. Tryptophan 101-104 gastrin releasing peptide Homo sapiens 17-29 2720119-6 1989 Finally, the marked dependence of tryptophan fluorescence quantum efficiency and order parameter from the hormone concentration in the presence of lysolecithin but not in buffer leads to the conclusion that bombesin can associate into the lipid matrix. Tryptophan 34-44 gastrin releasing peptide Homo sapiens 207-215 8496014-1 1993 Bombesin (Bn, pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2) is one of the most potent peptides, possessing a variety of physiological and pharmacological functions. Tryptophan 43-46 gastrin releasing peptide Homo sapiens 0-8