PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31680075-12	2019	Methadone hydrochloride induced apoptosis in HL-60 cells involved upregulation of Bid and caspase-8 expression and downregulation of Bcl-2, p21 and survivin expression.	Methadone	0-23	BH3 interacting domain death agonist	Homo sapiens	82-85	
23917673-3	2013	Ten opioid naive post-herpetic neuralgia patients received either methadone (5 mg bid) or placebo for three weeks, followed by a 15-day washout period and a second three-week treatment with either methadone or placebo, accordingly.	Methadone	66-75	BH3 interacting domain death agonist	Homo sapiens	82-85	
17074798-10	2007	Coadministration of 200 mg voriconazole BID with methadone was generally safe and well tolerated.	Methadone	49-58	BH3 interacting domain death agonist	Homo sapiens	40-43