PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12213451-1 2002 5-Substituted-1H-tetrazoles (RCN4H) are often used as metabolism-resistant isosteric replacements for carboxylic acids (RCO2H) in SAR-driven medicinal chemistry analogue syntheses. rco2h 120-125 sarcosine dehydrogenase Homo sapiens 130-133