PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2569235-4 1989 Studies of yeast mutants blocked in sterol biosynthesis demonstrated that the membrane association and biological activation of the yeast Ras2 protein require mevalonate, a precursor of sterols and other isoprenes such as farnesyl pyrophosphate. isoprene 204-213 Ras family GTPase RAS2 Saccharomyces cerevisiae S288C 138-142