PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12208470-7 2002 The effect of fluvastatin on IL-8 production was completely reversed in the presence of mevalonate or geranylgeranyl-pyrophosphate, but not in the presence of squalene or farnesyl-pyrophosphate. Mevalonic Acid 88-98 C-X-C motif chemokine ligand 8 Homo sapiens 29-33 16511915-9 2006 These effects of simvastatin on IL-6 and IL-8 production and cell proliferation were reversed in the presence of mevalonic acid or geranylgeranyl-pyrophosphate, but not with farnesyl-pyrophosphate. Mevalonic Acid 113-127 C-X-C motif chemokine ligand 8 Homo sapiens 41-45 8195701-0 1994 Role of the mevalonate pathway of isoprenoid synthesis in IL-8 generation by activated monocytic cells. Mevalonic Acid 12-22 C-X-C motif chemokine ligand 8 Homo sapiens 58-62 10917872-1 2000 Does inhibition of the mevalonate pathway lower interleukin-8 levels in the vessel wall? Mevalonic Acid 23-33 C-X-C motif chemokine ligand 8 Homo sapiens 48-61 8195701-6 1994 Coincubation of reductase inhibitor-treated cells with mevalonate prevented the attenuation of IL-8 production by reductase inhibitors. Mevalonic Acid 55-65 C-X-C motif chemokine ligand 8 Homo sapiens 95-99 8195701-9 1994 We conclude that isoprenoid generation through the mevalonate pathway is a requirement for IL-8 induction by activated monocytic cells in vitro. Mevalonic Acid 51-61 C-X-C motif chemokine ligand 8 Homo sapiens 91-95