PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17372087-0 2007 The influence of hyaluronan-CD44 interaction on topoisomerase II activity and etoposide cytotoxicity in head and neck cancer. Etoposide 78-87 CD44 molecule (Indian blood group) Homo sapiens 28-32 21935404-11 2011 Our results thus reveal that 1) not all DTCs are necessarily CSCs; 2) conventional chemotherapeutic drugs such as taxol and etoposide may directly target CD44(+) tumor-initiating cells; and 3) DTCs generated via chronic drug selection involve epigenetic mechanisms. Etoposide 124-133 CD44 molecule (Indian blood group) Homo sapiens 154-158 27009862-0 2016 Virtual screening-driven repositioning of etoposide as CD44 antagonist in breast cancer cells. Etoposide 42-51 CD44 molecule (Indian blood group) Homo sapiens 55-59 27009862-4 2016 Drugs that performed best in docking were examined in molecular dynamics simulations, identifying etoposide as a potential CD44 antagonist. Etoposide 98-107 CD44 molecule (Indian blood group) Homo sapiens 123-127 27009862-8 2016 Moreover, etoposide decreased the proportion of CD44+/CD24- cells, lowered chemoresistance, and blocked mammosphere formation. Etoposide 10-19 CD44 molecule (Indian blood group) Homo sapiens 48-52 27009862-9 2016 Our data indicate that etoposide blocks CD44 activation, impairing key cellular functions that drive malignancy, thus rendering it a candidate for further translational studies and a potential lead compound in the development of new CD44 antagonists. Etoposide 23-32 CD44 molecule (Indian blood group) Homo sapiens 40-44 27009862-9 2016 Our data indicate that etoposide blocks CD44 activation, impairing key cellular functions that drive malignancy, thus rendering it a candidate for further translational studies and a potential lead compound in the development of new CD44 antagonists. Etoposide 23-32 CD44 molecule (Indian blood group) Homo sapiens 233-237 12297287-4 2002 Cells expressing CD44 were significantly resistant to etoposide-induced apoptosis. Etoposide 54-63 CD44 molecule (Indian blood group) Homo sapiens 17-21 15215046-5 2004 Mock-transfected and CD44-transfected cells were exposed to etoposide to induce apoptosis. Etoposide 60-69 CD44 molecule (Indian blood group) Homo sapiens 21-25 15215046-7 2004 It was observed that resistance to apoptosis induced by etoposide is promoted by CD44 expression in SW620, and this resistance is better sustained by the full variant isoform, v3-10. Etoposide 56-65 CD44 molecule (Indian blood group) Homo sapiens 81-85 10910943-3 2000 Using 2 myeloid cell lines, HL60 and NB4, evidence is presented that prior incubation with the CD44-specific monoclonal antibody (mAb) A3D8, reported to induce differentiation of AML blasts, significantly decreases apoptosis induced by 3 drugs used in AML chemotherapy: daunorubicin (DNR), mitoxantrone, and etoposide. Etoposide 308-317 CD44 molecule (Indian blood group) Homo sapiens 95-99