PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33430646-6 2021 Intriguingly, a concomitant cell treatment with a selected SMURF2-targeting compound and the DNA-damaging drug etoposide markedly increased the cytotoxicity produced by this drug in growing cells. Etoposide 111-120 SMAD specific E3 ubiquitin protein ligase 2 Homo sapiens 59-65 28611047-7 2017 Smurf2 was a determinant of Topo IIalpha protein levels in normal and cancer cells and tissues, and its levels affected cell sensitivity to the Topo II-targeting drug etoposide. Etoposide 167-176 SMAD specific E3 ubiquitin protein ligase 2 Homo sapiens 0-6