PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34678222-9 2021 DFF40 deficient cells show chemoresistance to antimetabolites (e.g. methotrexate, 6-mercaptopurine and cytarabine) and surprisingly, they are more sensitive to TOP2 inhibitors (e.g. etoposide and teniposide). Etoposide 182-191 DNA fragmentation factor subunit beta Homo sapiens 0-5 34678222-11 2021 Etoposide exposure in DFF40 deficient cells induces higher mortality levels and downregulation of Bcl-xL cells compared to DFF40 expressing T cells. Etoposide 0-9 DNA fragmentation factor subunit beta Homo sapiens 22-27 34678222-12 2021 The abolition of DFF40 expression in Jurkat cells significantly impairs histone H2AX phosphorylation following etoposide and cytarabine treatments. Etoposide 111-120 DNA fragmentation factor subunit beta Homo sapiens 17-22