PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29953987-4 2018 In this study, we report whether Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG) enhanced etoposide-induced cytotoxicity in NSCLC cells through modulating the XPC expression. Etoposide 106-115 heat shock protein 90 alpha family class A member 1 Homo sapiens 33-38 16385570-7 2006 The Hsp90 inhibitors geldanamycin, 17-AAG (17-allylamino-17-demethoxygeldanamycin) and radicicol significantly enhanced the activity of the topoisomerase II poisons etoposide and mitoxantrone in vitro and in vivo. Etoposide 165-174 heat shock protein 90 alpha family class A member 1 Homo sapiens 4-9 29953987-8 2018 Hsp90 inhibitor 17-AAG enhanced cytotoxicity and cell growth inhibition of etoposide in NSCLC cells, which were associated with the downregulation of XPC expression and inactivation of AKT. Etoposide 75-84 heat shock protein 90 alpha family class A member 1 Homo sapiens 0-5 29953987-9 2018 Our findings suggested that the Hsp90 inhibition induced XPC downregulation involved in enhancing the etoposide-induced cytotoxicity in H1703 and H520 cells. Etoposide 102-111 heat shock protein 90 alpha family class A member 1 Homo sapiens 32-37 22053010-9 2012 Moreover, the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG) could decrease the etoposide-induced p38 MAPK-mediated ERCC1 expression and augment the cytotoxic effect and growth inhibition by etopsoside. Etoposide 97-106 heat shock protein 90 alpha family class A member 1 Homo sapiens 14-19