PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34887387-6 2021 Furthermore, we provide the first preclinical evidence demonstrating that combined therapy with a DOT1L inhibitor significantly improves the therapeutic efficacy of etoposide in murine orthotopic xenografts of RB by rendering the response to etoposide more potent and stable. Etoposide 165-174 DOT1-like, histone H3 methyltransferase (S. cerevisiae) Mus musculus 98-103 34887387-6 2021 Furthermore, we provide the first preclinical evidence demonstrating that combined therapy with a DOT1L inhibitor significantly improves the therapeutic efficacy of etoposide in murine orthotopic xenografts of RB by rendering the response to etoposide more potent and stable. Etoposide 242-251 DOT1-like, histone H3 methyltransferase (S. cerevisiae) Mus musculus 98-103