PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9242521-4 1997 Immunoblotting showed that treatment of wild-type Jurkat cells with anti-Fas or the topoisomerase II-directed agent etoposide resulted in proteolytic cleavage of precursors for the cysteine-dependent aspartate-directed proteases caspase-3 and caspase-7 and degradation of the caspase substrates poly(ADP-ribose) polymerase (PARP) and lamin B1. Etoposide 116-125 lamin B1 Homo sapiens 334-342