PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15388581-4 2005 Ectopic expression of hsp70 in HL-60 cells (HL-60/hsp70) inhibited Ara-C and etoposide-induced Bax conformation change and translocation to the mitochondria; attenuated the accumulation of cytochrome c, Smac, and Omi/HtrA2 in the cytosol; and inhibited the processing and activity of caspase-9 and caspase-3. Etoposide 77-86 HtrA serine peptidase 2 Homo sapiens 217-222 12835328-2 2003 Suppression of Omi/HtrA2 by RNA interference in human cell lines reduces cell death in response to TRAIL and etoposide. Etoposide 109-118 HtrA serine peptidase 2 Homo sapiens 19-24 35614109-4 2022 Apigenin when combined with etoposide or cyclophosphamide-induced apoptosis via the mitochondrial pathway, increasing the expression of pro-apoptotic cytochrome c, SMAC/DIABLO, and HTRA2/OMI, which promoted caspase-9 and -3 activation. Etoposide 28-37 HtrA serine peptidase 2 Homo sapiens 181-190