PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17302912-4 2007 Inhibition of phosphoinositide-3-kinase (PI3K)/Akt pathway with wortmannin or Akt small hairpin RNA (shRNA) abolished the ability of peroxynitrite to prevent etoposide-induced apoptotic death. Etoposide 158-167 AKT serine/threonine kinase 1 Rattus norvegicus 47-50 20177738-3 2010 In this study, VP-16-induced RBL-2H3 cells apoptosis was accompanied by the activation of Akt and ERK. Etoposide 15-20 AKT serine/threonine kinase 1 Rattus norvegicus 90-93 20177738-6 2010 Over expression of Cbl-b significantly enhanced VP-16-induced cell apoptosis with inhibition of Akt activity, while a dominant negative (DN) RING Finger domain mutation completely abolished this enhancement. Etoposide 48-53 AKT serine/threonine kinase 1 Rattus norvegicus 96-99 17302912-4 2007 Inhibition of phosphoinositide-3-kinase (PI3K)/Akt pathway with wortmannin or Akt small hairpin RNA (shRNA) abolished the ability of peroxynitrite to prevent etoposide-induced apoptotic death. Etoposide 158-167 AKT serine/threonine kinase 1 Rattus norvegicus 78-81 16644697-4 2006 2) Overexpression of a constitutively active form of the antiapoptotic protein kinase Akt1 in 832/13 cells provides significant protection against cell killing induced by camptothecin and etoposide but no protection against cytokine-mediated damage. Etoposide 188-197 AKT serine/threonine kinase 1 Rattus norvegicus 86-90 15887249-2 2005 Expression of a myristoylated constitutively active form of Akt (myr-Akt) in PC12 cells could override cell-growth arrest at G2/M phase and apoptosis that were induced by etoposide treatment. Etoposide 171-180 AKT serine/threonine kinase 1 Rattus norvegicus 60-63 15887249-2 2005 Expression of a myristoylated constitutively active form of Akt (myr-Akt) in PC12 cells could override cell-growth arrest at G2/M phase and apoptosis that were induced by etoposide treatment. Etoposide 171-180 AKT serine/threonine kinase 1 Rattus norvegicus 69-72 12700634-3 2003 Transduction of C5 cells with an adenovirus expressing a constitutively activated mutant of Akt-suppressed etoposide-induced apoptosis, whereas a kinase-inactive mutant of Akt suppressed the protective effect of IGF1. Etoposide 107-116 AKT serine/threonine kinase 1 Rattus norvegicus 92-95