PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15767545-0 2005 Suppression of RAD21 gene expression decreases cell growth and enhances cytotoxicity of etoposide and bleomycin in human breast cancer cells. Etoposide 88-97 RAD21 cohesin complex component Homo sapiens 15-20 21255398-11 2011 Knockdown of RAD21 in the MDA-MB-231 breast cancer cell line significantly enhanced sensitivity to cyclophosphamide, 5-fluorouracil and etoposide. Etoposide 136-145 RAD21 cohesin complex component Homo sapiens 13-18 15767545-7 2005 Moreover, MCF-7 cell sensitivity to two DNA-damaging chemotherapeutic agents, etoposide and bleomycin, was increased after inhibition of RAD21 expression with a dose reduction factor 50 (DRF50) of 1.42 and 3.71, respectively. Etoposide 78-87 RAD21 cohesin complex component Homo sapiens 137-142 15767545-8 2005 At the highest concentrations of etoposide and bleomycin administered, cells transfected with a single siRNA duplex targeted against RAD21 showed 57% and 60% survival as compared with control cells, respectively. Etoposide 33-42 RAD21 cohesin complex component Homo sapiens 133-138