PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22224417-4 2012 In vivo, focal application of 100 muM d-kynurenine by reverse microdialysis led to a steady rise in extracellular kynurenic acid in the rat striatum, causing a 4-fold elevation after 2 h. Attesting to functional significance, this increase was accompanied by a 36% reduction in extracellular dopamine. Kynurenic Acid 114-128 latexin Homo sapiens 34-37 18799828-2 2008 Clenbuterol enhanced the production of kynurenic acid in brain cortical slices (0.1-1.0 mM) and in glial cultures (1-50 muM). Kynurenic Acid 39-53 latexin Homo sapiens 120-123 22108572-4 2012 The apparent 50% inhibitory concentrations of kynurenic acid were estimated to be 12.9 muM for hOAT1, and 7.76 muM for hOAT3. Kynurenic Acid 46-60 latexin Homo sapiens 87-90 22108572-4 2012 The apparent 50% inhibitory concentrations of kynurenic acid were estimated to be 12.9 muM for hOAT1, and 7.76 muM for hOAT3. Kynurenic Acid 46-60 latexin Homo sapiens 111-114 22108572-5 2012 Both hOAT1 and hOAT3 markedly stimulated the uptake of kynurenic acid into oocytes, and the K(m) values of the transport were calculated to be 5.06 muM and 4.86 muM, respectively. Kynurenic Acid 55-69 latexin Homo sapiens 148-151 22108572-5 2012 Both hOAT1 and hOAT3 markedly stimulated the uptake of kynurenic acid into oocytes, and the K(m) values of the transport were calculated to be 5.06 muM and 4.86 muM, respectively. Kynurenic Acid 55-69 latexin Homo sapiens 161-164