PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27131920-0	2016	Kynurenic acid and zaprinast induce analgesia by modulating HCN channels through GPR35 activation.	Kynurenic Acid	0-14	G protein-coupled receptor 35	Rattus norvegicus	81-86	
30988385-2	2019	One of the factors recently recognized to influence metabolism and weight gain is kynurenic acid (KYNA), an agonist of G protein-coupled receptor (GPR35).	Kynurenic Acid	82-96	G protein-coupled receptor 35	Rattus norvegicus	147-152	
30988385-2	2019	One of the factors recently recognized to influence metabolism and weight gain is kynurenic acid (KYNA), an agonist of G protein-coupled receptor (GPR35).	Kynurenic Acid	98-102	G protein-coupled receptor 35	Rattus norvegicus	147-152	
27131920-6	2016	We found that both kynurenic acid (KYNA) and zaprinast, the endogenous and synthetic GPR35 agonist respectively, were able to antagonize the forskolin-induced depolarization of resting membrane potential by reducing Ih-mediated depolarization.	Kynurenic Acid	19-33	G protein-coupled receptor 35	Rattus norvegicus	85-90	
27131920-6	2016	We found that both kynurenic acid (KYNA) and zaprinast, the endogenous and synthetic GPR35 agonist respectively, were able to antagonize the forskolin-induced depolarization of resting membrane potential by reducing Ih-mediated depolarization.	Kynurenic Acid	35-39	G protein-coupled receptor 35	Rattus norvegicus	85-90	
25542997-1	2015	The G-protein-coupled receptor 35 (GPR35) was de-orphanized after the discovery that kynurenic acid (KYNA), an endogenous tryptophan metabolite, acts as an agonist of this receptor.	Kynurenic Acid	85-99	G protein-coupled receptor 35	Rattus norvegicus	35-40	
25542997-1	2015	The G-protein-coupled receptor 35 (GPR35) was de-orphanized after the discovery that kynurenic acid (KYNA), an endogenous tryptophan metabolite, acts as an agonist of this receptor.	Kynurenic Acid	85-99	G protein-coupled receptor 35	Rattus norvegicus	4-33	
18235993-1	2008	Kynurenic acid is an antagonist of glutamate and alpha-7 nicotinic acetylcholine receptors and an agonist of the G: -protein-coupled receptor GPR35, which is predominantly expressed in immune and gastrointestinal tissues.	Kynurenic Acid	0-14	G protein-coupled receptor 35	Rattus norvegicus	142-147	
24312407-0	2013	GPR35 activation reduces Ca2+ transients and contributes to the kynurenic acid-dependent reduction of synaptic activity at CA3-CA1 synapses.	Kynurenic Acid	64-78	G protein-coupled receptor 35	Rattus norvegicus	0-5	
24312407-1	2013	Limited information is available on the brain expression and role of GPR35, a Gi/o coupled receptor activated by kynurenic acid (KYNA).	Kynurenic Acid	113-127	G protein-coupled receptor 35	Rattus norvegicus	69-74	
18235993-2	2008	In this study, we report that kynurenic acid is present in the lumen of rat small intestine in micromolar concentration sufficient to affect the GPR35 receptor.	Kynurenic Acid	30-44	G protein-coupled receptor 35	Rattus norvegicus	145-150	
17940199-2	2008	From these screens, kynurenic acid, an endogenous metabolite of tryptophan, and zaprinast, a synthetic inhibitor of cyclic guanosine monophosphate-specific phosphodiesterase, emerged as potential agonists for GPR35.	Kynurenic Acid	20-34	G protein-coupled receptor 35	Rattus norvegicus	209-214	
17996730-1	2008	GPR35, previously an orphan G-protein coupled receptor, is a receptor for kynurenic acid.	Kynurenic Acid	74-88	G protein-coupled receptor 35	Rattus norvegicus	0-5	
17996730-5	2008	The GPR35 agonists kynurenic acid and zaprinast inhibited forskolin-stimulated cAMP production by cultured rat DRG neurons.	Kynurenic Acid	19-33	G protein-coupled receptor 35	Rattus norvegicus	4-9