PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32219734-4 2020 In the present study, we try to determine the neuroprotective capacity of KYNA on the QUIN effects in redox homeostasis changes (H2DCF oxidation, superoxide dismutase/catalase (SOD/CAT) ratio, glutathione peroxidase (GPx) activity, sulfhydryl content, and nitrite levels), as well as on inflammatory parameters (levels of TNF-alpha, IL-1beta, and IL-6). Kynurenic Acid 74-78 interleukin 1 alpha Rattus norvegicus 333-341 32219734-7 2020 Results demonstrated that the KYNA administration was able to prevent the increase in reactive oxygen species, SOD/CAT ratio, and pro-inflammatory cytokines (IL-1beta and IL-6) and the decrease in GPx activity, sulfhydryl content, and nitrite levels caused by QUIN. Kynurenic Acid 30-34 interleukin 1 alpha Rattus norvegicus 158-166 34475875-12 2021 Plasma levels of CitH3, MPO and IL-1beta were elevated in sepsis but were ameliorated by KYNA and its synthetic analogues. Kynurenic Acid 89-93 interleukin 1 alpha Rattus norvegicus 32-40