PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8906269-0	1996	Kynurenic acid-enhancing and anti-ischemic effects of the potent kynurenine 3-hydroxylase inhibitor FCE 28833 in rodents.	Kynurenic Acid	0-14	kynurenine 3-monooxygenase	Homo sapiens	65-89	
25540092-13	2014	In both reactive and secondary depression, the balance between 3-hydroxykynurenine (3-HK) and kynurenic acid may shift towards 3-HK production via kynurenine-3-monooxygenase (KMO) activation.	Kynurenic Acid	94-108	kynurenine 3-monooxygenase	Homo sapiens	147-173	
25540092-13	2014	In both reactive and secondary depression, the balance between 3-hydroxykynurenine (3-HK) and kynurenic acid may shift towards 3-HK production via kynurenine-3-monooxygenase (KMO) activation.	Kynurenic Acid	94-108	kynurenine 3-monooxygenase	Homo sapiens	175-178	
21693093-0	2012	Kynurenine 3-monooxygenase polymorphisms: relevance for kynurenic acid synthesis in patients with  schizophrenia and healthy controls.	Kynurenic Acid	56-70	kynurenine 3-monooxygenase	Homo sapiens	0-26	
12354294-1	2002	Kynurenine 3-mono-oxygenase (KMO) inhibitors reduce 3-hydroxykynurenine (3-HK) and quinolinic acid (QUIN) neosynthesis and facilitate kynurenine metabolism towards kynurenic acid (KYNA) formation.	Kynurenic Acid	164-178	kynurenine 3-monooxygenase	Homo sapiens	0-27	
12354294-1	2002	Kynurenine 3-mono-oxygenase (KMO) inhibitors reduce 3-hydroxykynurenine (3-HK) and quinolinic acid (QUIN) neosynthesis and facilitate kynurenine metabolism towards kynurenic acid (KYNA) formation.	Kynurenic Acid	164-178	kynurenine 3-monooxygenase	Homo sapiens	29-32	
19226371-1	2009	In the mammalian brain, kynurenine aminotransferase II (KAT II) and kynurenine 3-monooxygenase (KMO), key enzymes of the kynurenine pathway (KP) of tryptophan degradation, form the neuroactive metabolites kynurenic acid (KYNA) and 3-hydroxykynurenine (3-HK), respectively.	Kynurenic Acid	205-219	kynurenine 3-monooxygenase	Homo sapiens	68-94	
19226371-1	2009	In the mammalian brain, kynurenine aminotransferase II (KAT II) and kynurenine 3-monooxygenase (KMO), key enzymes of the kynurenine pathway (KP) of tryptophan degradation, form the neuroactive metabolites kynurenic acid (KYNA) and 3-hydroxykynurenine (3-HK), respectively.	Kynurenic Acid	205-219	kynurenine 3-monooxygenase	Homo sapiens	96-99	
19226371-1	2009	In the mammalian brain, kynurenine aminotransferase II (KAT II) and kynurenine 3-monooxygenase (KMO), key enzymes of the kynurenine pathway (KP) of tryptophan degradation, form the neuroactive metabolites kynurenic acid (KYNA) and 3-hydroxykynurenine (3-HK), respectively.	Kynurenic Acid	221-225	kynurenine 3-monooxygenase	Homo sapiens	68-94	
19226371-1	2009	In the mammalian brain, kynurenine aminotransferase II (KAT II) and kynurenine 3-monooxygenase (KMO), key enzymes of the kynurenine pathway (KP) of tryptophan degradation, form the neuroactive metabolites kynurenic acid (KYNA) and 3-hydroxykynurenine (3-HK), respectively.	Kynurenic Acid	221-225	kynurenine 3-monooxygenase	Homo sapiens	96-99	
15206781-2	2003	A novel potent and selective kynurenine-3-hydroxylase inhibitor is descibed along a preliminary evaluation in a in vivo gerbil model of its ability to increase the kynurenine and kynurenic acid concentration in both plasma and brain.	Kynurenic Acid	179-193	kynurenine 3-monooxygenase	Homo sapiens	29-53	
33275878-3	2021	The inhibition of KMO reduces the production of downstream toxic kynurenine pathway metabolites and shifts the flux to the formation of the neuroprotectant kynurenic acid.	Kynurenic Acid	156-170	kynurenine 3-monooxygenase	Homo sapiens	18-21	
28187857-2	2017	Possibly as a result of reduced kynurenine 3-monooxygenase activity, elevated central nervous system levels of kynurenic acid have been found in patients with psychotic disorders, including schizophrenia.	Kynurenic Acid	111-125	kynurenine 3-monooxygenase	Homo sapiens	32-58	
32148781-3	2020	KMO controlling the chief division of the KP, which directly controls downstream product quinolinic acid (QUIN) and indirectly controls kynurenic acid (KYNA), plays an important role in many diseases, especially neurological diseases.	Kynurenic Acid	136-150	kynurenine 3-monooxygenase	Homo sapiens	0-3	
32148781-3	2020	KMO controlling the chief division of the KP, which directly controls downstream product quinolinic acid (QUIN) and indirectly controls kynurenic acid (KYNA), plays an important role in many diseases, especially neurological diseases.	Kynurenic Acid	152-156	kynurenine 3-monooxygenase	Homo sapiens	0-3	
27245499-5	2017	Contributing to enhanced production of kynurenic acid, the expression and enzyme activity of kynurenine 3-monooxygenase (KMO) are reduced in schizophrenia and in bipolar patients with a history of psychosis.	Kynurenic Acid	39-53	kynurenine 3-monooxygenase	Homo sapiens	93-119	
27245499-5	2017	Contributing to enhanced production of kynurenic acid, the expression and enzyme activity of kynurenine 3-monooxygenase (KMO) are reduced in schizophrenia and in bipolar patients with a history of psychosis.	Kynurenic Acid	39-53	kynurenine 3-monooxygenase	Homo sapiens	121-124