PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14678248-8 2003 Cytochrome P450 (CYP) isoform-specific chemical and monoclonal antibody inhibition studies have demonstrated that CYP2B6, CYP2C9, CYP2D6 and CYP3A4 all mediate the formation of Z-4-OH-tam. z-4-oh-tam 177-187 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 0-15 14678248-8 2003 Cytochrome P450 (CYP) isoform-specific chemical and monoclonal antibody inhibition studies have demonstrated that CYP2B6, CYP2C9, CYP2D6 and CYP3A4 all mediate the formation of Z-4-OH-tam. z-4-oh-tam 177-187 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 17-20 14678248-10 2003 Significant associations between the percentage inhibition of Z-4-OH-tam by CYP isoform-specific inhibitors and the rate of metabolism of CYP isoform-specific index reactions and between individual expression of CYP2B6, CYP2C9 and CYP2D6 and Z-4-OH-tam formation rates indicate predominant roles for these isoforms in this pathway. z-4-oh-tam 62-72 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 76-79 14678248-10 2003 Significant associations between the percentage inhibition of Z-4-OH-tam by CYP isoform-specific inhibitors and the rate of metabolism of CYP isoform-specific index reactions and between individual expression of CYP2B6, CYP2C9 and CYP2D6 and Z-4-OH-tam formation rates indicate predominant roles for these isoforms in this pathway. z-4-oh-tam 62-72 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 138-141 14678248-10 2003 Significant associations between the percentage inhibition of Z-4-OH-tam by CYP isoform-specific inhibitors and the rate of metabolism of CYP isoform-specific index reactions and between individual expression of CYP2B6, CYP2C9 and CYP2D6 and Z-4-OH-tam formation rates indicate predominant roles for these isoforms in this pathway. z-4-oh-tam 242-252 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 76-79 14678248-10 2003 Significant associations between the percentage inhibition of Z-4-OH-tam by CYP isoform-specific inhibitors and the rate of metabolism of CYP isoform-specific index reactions and between individual expression of CYP2B6, CYP2C9 and CYP2D6 and Z-4-OH-tam formation rates indicate predominant roles for these isoforms in this pathway. z-4-oh-tam 242-252 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 138-141