PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8469771-5	1993	In both skin and liver, 2 mM dithiothreitol enhanced the binding of AT2 receptors by increasing receptor affinity, but inhibited binding of AT1 by decreasing the receptor number.	Dithiothreitol	29-43	angiotensin II receptor, type 1a	Rattus norvegicus	140-143	
8065468-1	1994	The disulfide-reducing agent dithiothreitol (DTT) has been shown to reduce angiotensin II (Ang II) subtype 1 receptor (AT1) binding sites in various tissues.	Dithiothreitol	29-43	angiotensin II receptor, type 1a	Rattus norvegicus	75-122	
8065468-1	1994	The disulfide-reducing agent dithiothreitol (DTT) has been shown to reduce angiotensin II (Ang II) subtype 1 receptor (AT1) binding sites in various tissues.	Dithiothreitol	45-48	angiotensin II receptor, type 1a	Rattus norvegicus	75-122	
1329044-2	1992	The AT1 antagonist DuP 753 competed for ANG binding with high affinity; binding was abolished by dithiothreitol.	Dithiothreitol	97-111	angiotensin II receptor, type 1a	Rattus norvegicus	4-7	
1279763-5	1992	In addition, the reducing agent, dithiothreitol, produces a dose-dependent inhibition of Ang II receptor binding with an IC50 of 2 mM, a characteristic of the AT1 receptors.	Dithiothreitol	33-47	angiotensin II receptor, type 1a	Rattus norvegicus	159-162	
1913722-3	1991	The reducing agent dithiothreitol decreased the binding to AT-1 receptors and enhanced the binding to AT-2 receptors.	Dithiothreitol	19-33	angiotensin II receptor, type 1a	Rattus norvegicus	59-63	
19039312-4	2009	RESULTS: Preincubation of cells with DTT, a maneuver designed to target receptor disulfides, resulted in concentration-dependent decreases in specific (125)I-AngII binding to AT1Rs and acute angiotensin-stimulated intracellular calcium mobilization but no decreases in specific (125)I-AVP binding to V1Rs or AVP-stimulated intracellular calcium mobilization.	Dithiothreitol	37-40	angiotensin II receptor, type 1a	Rattus norvegicus	175-178