PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22971010-9	2012	Thiol reduction with dithiothreitol decreased HIF-1alpha stabilization in hypoxic cells, while dinitrochlorobenzene, which stabilizes S-nitrosothiols, favored its accumulation.	Dithiothreitol	21-35	hypoxia inducible factor 1 subunit alpha	Homo sapiens	46-56	
17541013-7	2007	Dithiothreitol blocked GSNO-induced Akt kinase activity and HIF-1alpha stabilization.	Dithiothreitol	0-14	hypoxia inducible factor 1 subunit alpha	Homo sapiens	60-70	
7626069-3	1995	Here, we provide evidence that alteration of cellular redox states by treating cells with H2O2 or dithiothreitol impairs hypoxia signaling mechanisms and the expression of HIF-1 alpha protein in hypoxic cells.	Dithiothreitol	98-112	hypoxia inducible factor 1 subunit alpha	Homo sapiens	172-183	
27780722-12	2018	The stimulatory effect of GSNO on VEGF was reversed not only by 2-ME but also by the denitrosylating agent dithiothreitol, confirming our hypothesis that GSNO"s benefits are mediated by the stabilization of HIF-1alpha via S-nitrosylation.	Dithiothreitol	107-121	hypoxia inducible factor 1 subunit alpha	Homo sapiens	207-217