PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25468822-9 2014 Furthermore, G226 (0.125-2 mumol/L) dose-dependently elevated the intracellular levels of H2O2 and in the cancer cells, and pretreatment with GSH, NAC or DTT not only blocked G226-induced intracellular accumulation of ROS, but also abrogated G226-mediated phosphorylation of H2AX, apoptosis and cytotoxicity. Dithiothreitol 154-157 H2A.X variant histone Homo sapiens 275-279