PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14554103-3 2003 Substantial differences in DTT influence on mitochondrial respiration at low and high [Cd2+] were revealed, namely, an enhanced mitochondrial permeabilization in the presence of saturated [DTT] at high [Cd2+] took place. Dithiothreitol 189-192 Cd2 molecule Rattus norvegicus 87-90 15560892-7 2004 High [NEM] promoted synergistic increase of the Cd2+-produced swelling in NH4NO3 medium; all above effects were reversed (and prevented) by dithiothreitol, DTT. Dithiothreitol 140-154 Cd2 molecule Rattus norvegicus 48-51 15560892-7 2004 High [NEM] promoted synergistic increase of the Cd2+-produced swelling in NH4NO3 medium; all above effects were reversed (and prevented) by dithiothreitol, DTT. Dithiothreitol 156-159 Cd2 molecule Rattus norvegicus 48-51 15560892-8 2004 We shown also that when exogenous Ca2+ and Pi were simultaneously present in NH4NO3 medium, DTT reversed only partially Cd2+-produced swelling of succinate plus rotenone-energized mitochondria, while DTT recovery action was complete when either Ca2+ or Pi were separately administered to the Cd2+-treated mitochondria. Dithiothreitol 92-95 Cd2 molecule Rattus norvegicus 120-123 15560892-8 2004 We shown also that when exogenous Ca2+ and Pi were simultaneously present in NH4NO3 medium, DTT reversed only partially Cd2+-produced swelling of succinate plus rotenone-energized mitochondria, while DTT recovery action was complete when either Ca2+ or Pi were separately administered to the Cd2+-treated mitochondria. Dithiothreitol 92-95 Cd2 molecule Rattus norvegicus 292-295 15560892-9 2004 Besides, DTT added following a low Cd2+ pulse in KCl medium containing exogenous Ca2+ induced a substantial enhancing of sustained Cd2+ stimulation of mitochondrial basal respiration and the stimulation was CsA-sensitive, while the activation promoted by low [Cd2+] alone was totally eliminated by DTT supplement. Dithiothreitol 9-12 Cd2 molecule Rattus norvegicus 35-38 15560892-9 2004 Besides, DTT added following a low Cd2+ pulse in KCl medium containing exogenous Ca2+ induced a substantial enhancing of sustained Cd2+ stimulation of mitochondrial basal respiration and the stimulation was CsA-sensitive, while the activation promoted by low [Cd2+] alone was totally eliminated by DTT supplement. Dithiothreitol 9-12 Cd2 molecule Rattus norvegicus 131-134 15560892-9 2004 Besides, DTT added following a low Cd2+ pulse in KCl medium containing exogenous Ca2+ induced a substantial enhancing of sustained Cd2+ stimulation of mitochondrial basal respiration and the stimulation was CsA-sensitive, while the activation promoted by low [Cd2+] alone was totally eliminated by DTT supplement. Dithiothreitol 9-12 Cd2 molecule Rattus norvegicus 131-134 15560892-9 2004 Besides, DTT added following a low Cd2+ pulse in KCl medium containing exogenous Ca2+ induced a substantial enhancing of sustained Cd2+ stimulation of mitochondrial basal respiration and the stimulation was CsA-sensitive, while the activation promoted by low [Cd2+] alone was totally eliminated by DTT supplement. Dithiothreitol 298-301 Cd2 molecule Rattus norvegicus 131-134 15560892-9 2004 Besides, DTT added following a low Cd2+ pulse in KCl medium containing exogenous Ca2+ induced a substantial enhancing of sustained Cd2+ stimulation of mitochondrial basal respiration and the stimulation was CsA-sensitive, while the activation promoted by low [Cd2+] alone was totally eliminated by DTT supplement. Dithiothreitol 298-301 Cd2 molecule Rattus norvegicus 131-134 14554103-2 2003 In particular, EGTA, ADP, and cyclosporin A (potent mitochondrial permeability transition antagonists) affected mainly Cd2+-induced changes in resting state respiration, eliminating its stimulation in KCl medium, while dithiothreitol (DTT, a dithiol reductant) produced its effect both on Cd2+ activation of the basal respiration and Cd2+ depression of uncoupler-stimulated respiration, evoking its restoration. Dithiothreitol 235-238 Cd2 molecule Rattus norvegicus 119-122 14554103-3 2003 Substantial differences in DTT influence on mitochondrial respiration at low and high [Cd2+] were revealed, namely, an enhanced mitochondrial permeabilization in the presence of saturated [DTT] at high [Cd2+] took place. Dithiothreitol 27-30 Cd2 molecule Rattus norvegicus 87-90 14554103-3 2003 Substantial differences in DTT influence on mitochondrial respiration at low and high [Cd2+] were revealed, namely, an enhanced mitochondrial permeabilization in the presence of saturated [DTT] at high [Cd2+] took place. Dithiothreitol 27-30 Cd2 molecule Rattus norvegicus 203-206 14554103-4 2003 Besides, DTT only partially reversed Cd2+-induced swelling in NH4NO3 medium when glutamate plus malate or succinate without rotenone was used. Dithiothreitol 9-12 Cd2 molecule Rattus norvegicus 37-40 10413299-10 1999 The reducing reagent dithiothreitol, which alone was unable to modify [3H]CCPA binding, overcame the inhibiting effects of both Cd2+ and DTNB. Dithiothreitol 21-35 Cd2 molecule Rattus norvegicus 128-131 1397500-4 1992 The effect of Cd2+ on the GR binding activity can be reversed with DTT, suggesting Cd2+ interaction with thiol groups. Dithiothreitol 67-70 Cd2 molecule Rattus norvegicus 14-17 8137886-2 1994 Five millimolar dithiothreitol reversed the rather stable block of the specific binding produced by Cd2+ or Zn2+. Dithiothreitol 16-30 Cd2 molecule Rattus norvegicus 100-103 1397500-4 1992 The effect of Cd2+ on the GR binding activity can be reversed with DTT, suggesting Cd2+ interaction with thiol groups. Dithiothreitol 67-70 Cd2 molecule Rattus norvegicus 83-86 1839962-4 1991 The effect of Cd2+ is reversible by 1 mM cysteine or dithiothreitol (DTT). Dithiothreitol 53-67 Cd2 molecule Rattus norvegicus 14-17 1839962-4 1991 The effect of Cd2+ is reversible by 1 mM cysteine or dithiothreitol (DTT). Dithiothreitol 69-72 Cd2 molecule Rattus norvegicus 14-17