PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34479994-5 2021 Next, we investigated a model for spinocerebellar ataxia type 1 (SCA1) driven by the transgenic expression of the expanded Ataxin 1 protein with 82 glutamine (82Q), exhibiting severe PC degeneration in the anterior cerebellum while the flocculonodular region is preserved. Glutamine 148-157 ataxin 1 Mus musculus 123-131 17322884-1 2007 Spinocerebellar ataxia type 1 (SCA1) is a dominantly inherited neurodegenerative disease caused by expansion of a glutamine tract in ataxin-1 (ATXN1). Glutamine 114-123 ataxin 1 Mus musculus 0-29 17322884-1 2007 Spinocerebellar ataxia type 1 (SCA1) is a dominantly inherited neurodegenerative disease caused by expansion of a glutamine tract in ataxin-1 (ATXN1). Glutamine 114-123 ataxin 1 Mus musculus 31-35 17322884-1 2007 Spinocerebellar ataxia type 1 (SCA1) is a dominantly inherited neurodegenerative disease caused by expansion of a glutamine tract in ataxin-1 (ATXN1). Glutamine 114-123 ataxin 1 Mus musculus 133-141 17322884-1 2007 Spinocerebellar ataxia type 1 (SCA1) is a dominantly inherited neurodegenerative disease caused by expansion of a glutamine tract in ataxin-1 (ATXN1). Glutamine 114-123 ataxin 1 Mus musculus 143-148 17322884-2 2007 SCA1 pathogenesis studies support a model in which the expanded glutamine tract causes toxicity by modulating the normal activities of ATXN1. Glutamine 64-73 ataxin 1 Mus musculus 0-4 17322884-2 2007 SCA1 pathogenesis studies support a model in which the expanded glutamine tract causes toxicity by modulating the normal activities of ATXN1. Glutamine 64-73 ataxin 1 Mus musculus 135-140 20869591-3 2010 Here, we show that replacing Ser776 with a phosphomimicking Asp converted ATXN1 with a wild-type glutamine tract into a pathogenic protein. Glutamine 97-106 ataxin 1 Mus musculus 74-79 8789437-1 1996 Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disorder caused by the expansion of a CAG trinucleotide repeat which encodes glutamine in the novel protein ataxin-1. Glutamine 157-166 ataxin 1 Mus musculus 0-29 8789437-1 1996 Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disorder caused by the expansion of a CAG trinucleotide repeat which encodes glutamine in the novel protein ataxin-1. Glutamine 157-166 ataxin 1 Mus musculus 31-35 8789437-1 1996 Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disorder caused by the expansion of a CAG trinucleotide repeat which encodes glutamine in the novel protein ataxin-1. Glutamine 157-166 ataxin 1 Mus musculus 188-196 29427101-5 2018 Glutamine-expanded ATXN1 is highly stable and more resistant to degradation. Glutamine 0-9 ataxin 1 Mus musculus 19-24 33436887-1 2021 Spinocerebellar ataxia type 1 (SCA1) is a fatal neurodegenerative disease caused by abnormal expansion of glutamine-encoding CAG repeats in the Ataxin-1 (ATXN1) gene. Glutamine 106-115 ataxin 1 Mus musculus 0-29 33436887-1 2021 Spinocerebellar ataxia type 1 (SCA1) is a fatal neurodegenerative disease caused by abnormal expansion of glutamine-encoding CAG repeats in the Ataxin-1 (ATXN1) gene. Glutamine 106-115 ataxin 1 Mus musculus 31-35 33436887-1 2021 Spinocerebellar ataxia type 1 (SCA1) is a fatal neurodegenerative disease caused by abnormal expansion of glutamine-encoding CAG repeats in the Ataxin-1 (ATXN1) gene. Glutamine 106-115 ataxin 1 Mus musculus 144-152 33436887-1 2021 Spinocerebellar ataxia type 1 (SCA1) is a fatal neurodegenerative disease caused by abnormal expansion of glutamine-encoding CAG repeats in the Ataxin-1 (ATXN1) gene. Glutamine 106-115 ataxin 1 Mus musculus 154-159 32878998-2 2020 Mutant forms of ataxin-1 containing expanded glutamine stretches cause the movement disorder spinocerebellar ataxia type 1 (SCA1) through a toxic gain-of-function mechanism in the cerebellum. Glutamine 45-54 ataxin 1 Mus musculus 16-24 32878998-2 2020 Mutant forms of ataxin-1 containing expanded glutamine stretches cause the movement disorder spinocerebellar ataxia type 1 (SCA1) through a toxic gain-of-function mechanism in the cerebellum. Glutamine 45-54 ataxin 1 Mus musculus 124-128 24930030-1 2014 Spinocerebellar ataxia 1 (SCA1) results from pathologic glutamine expansion in the ataxin-1 protein (ATXN1). Glutamine 56-65 ataxin 1 Mus musculus 83-91 24930030-1 2014 Spinocerebellar ataxia 1 (SCA1) results from pathologic glutamine expansion in the ataxin-1 protein (ATXN1). Glutamine 56-65 ataxin 1 Mus musculus 101-106 24594842-1 2014 Spinocerebellar ataxia type 1 (SCA1) is an incurable neurodegenerative disease caused by a pathogenic glutamine repeat expansion in the protein ataxin-1 (ATXN1). Glutamine 102-111 ataxin 1 Mus musculus 0-29 24594842-1 2014 Spinocerebellar ataxia type 1 (SCA1) is an incurable neurodegenerative disease caused by a pathogenic glutamine repeat expansion in the protein ataxin-1 (ATXN1). Glutamine 102-111 ataxin 1 Mus musculus 31-35 24594842-1 2014 Spinocerebellar ataxia type 1 (SCA1) is an incurable neurodegenerative disease caused by a pathogenic glutamine repeat expansion in the protein ataxin-1 (ATXN1). Glutamine 102-111 ataxin 1 Mus musculus 144-152 24594842-1 2014 Spinocerebellar ataxia type 1 (SCA1) is an incurable neurodegenerative disease caused by a pathogenic glutamine repeat expansion in the protein ataxin-1 (ATXN1). Glutamine 102-111 ataxin 1 Mus musculus 154-159 22884877-1 2012 Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disease that results from a pathogenic glutamine-repeat expansion in the protein ataxin-1 (ATXN1). Glutamine 119-128 ataxin 1 Mus musculus 0-29 22884877-1 2012 Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disease that results from a pathogenic glutamine-repeat expansion in the protein ataxin-1 (ATXN1). Glutamine 119-128 ataxin 1 Mus musculus 31-35 22884877-1 2012 Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disease that results from a pathogenic glutamine-repeat expansion in the protein ataxin-1 (ATXN1). Glutamine 119-128 ataxin 1 Mus musculus 161-169 22884877-1 2012 Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disease that results from a pathogenic glutamine-repeat expansion in the protein ataxin-1 (ATXN1). Glutamine 119-128 ataxin 1 Mus musculus 171-176 22001907-1 2011 Spinocerebellar ataxia type 1 (SCA1) is an adult-onset, dominantly inherited neurodegenerative disease caused by expansion of a glutamine repeat tract in ataxin-1 (ATXN1). Glutamine 128-137 ataxin 1 Mus musculus 0-29 22001907-1 2011 Spinocerebellar ataxia type 1 (SCA1) is an adult-onset, dominantly inherited neurodegenerative disease caused by expansion of a glutamine repeat tract in ataxin-1 (ATXN1). Glutamine 128-137 ataxin 1 Mus musculus 31-35 22001907-1 2011 Spinocerebellar ataxia type 1 (SCA1) is an adult-onset, dominantly inherited neurodegenerative disease caused by expansion of a glutamine repeat tract in ataxin-1 (ATXN1). Glutamine 128-137 ataxin 1 Mus musculus 154-162 22001907-1 2011 Spinocerebellar ataxia type 1 (SCA1) is an adult-onset, dominantly inherited neurodegenerative disease caused by expansion of a glutamine repeat tract in ataxin-1 (ATXN1). Glutamine 128-137 ataxin 1 Mus musculus 164-169