PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3404287-1 1988 Sulfite oxidase catalyzes the oxidation of sulfite to sulfate. Sulfites 43-50 sulfite oxidase Rattus norvegicus 0-15 9389-7 1976 Kinetic studies on the reduction of the heme and tungsten centers of sulfite oxidase have shown that reduction of de-molybdo forms of sulfite oxidase by sulfite is catalyzed by the residual traces of native molybdenum-containing molecules. Sulfites 69-76 sulfite oxidase Rattus norvegicus 134-149 28529047-0 2017 Bezafibrate prevents mitochondrial dysfunction, antioxidant system disturbance, glial reactivity and neuronal damage induced by sulfite administration in striatum of rats: Implications for a possible therapeutic strategy for sulfite oxidase deficiency. Sulfites 128-135 sulfite oxidase Rattus norvegicus 225-240 25777939-1 2015 Sulfite oxidase (SOX) deficiency is an inherited neurometabolic disorder biochemically characterized by tissue accumulation and high urinary excretion of sulfite and thiosulfate. Sulfites 154-161 sulfite oxidase Rattus norvegicus 0-15 27523630-1 2016 Patients affected by sulfite oxidase (SO) deficiency present severe seizures early in infancy and progressive neurological damage, as well as tissue accumulation of sulfite, thiosulfate and S-sulfocysteine. Sulfites 21-28 sulfite oxidase Rattus norvegicus 38-40 27523630-5 2016 Sulfite decreased reduced glutathione concentrations and the activities of glutathione reductase and glutathione S-transferase (GST) in cerebral cortex and of GST in cerebellum of SO-deficient rats. Sulfites 0-7 sulfite oxidase Rattus norvegicus 180-182 27523630-6 2016 Moreover, sulfite increased the activities of complexes II and II-III in striatum and of complex II in hippocampus, but reduced the activity of complex IV in striatum of SO-deficient rats. Sulfites 10-17 sulfite oxidase Rattus norvegicus 170-172 27523630-8 2016 Finally, sulfite inhibited the activities of malate and glutamate dehydrogenase in cerebral cortex of SO-deficient rats. Sulfites 9-16 sulfite oxidase Rattus norvegicus 102-104 25342669-1 2016 Sulfite, commonly used as a preservative in foods, beverages, and pharmaceuticals, is a very reactive and potentially toxic molecule which is detoxified by sulfite oxidase (SOX). Sulfites 0-7 sulfite oxidase Rattus norvegicus 156-171 25342669-1 2016 Sulfite, commonly used as a preservative in foods, beverages, and pharmaceuticals, is a very reactive and potentially toxic molecule which is detoxified by sulfite oxidase (SOX). Sulfites 0-7 sulfite oxidase Rattus norvegicus 173-176 25777939-1 2015 Sulfite oxidase (SOX) deficiency is an inherited neurometabolic disorder biochemically characterized by tissue accumulation and high urinary excretion of sulfite and thiosulfate. Sulfites 154-161 sulfite oxidase Rattus norvegicus 17-20 20571963-3 2010 Sulfite is a very reactive and potentially toxic molecule and has to be detoxified by the enzyme sulfite oxidase (SOX). Sulfites 0-7 sulfite oxidase Rattus norvegicus 97-112 20571963-11 2010 When SOX-deficient rats treated with sulfite, TBARS level was still higher than other groups. Sulfites 37-44 sulfite oxidase Rattus norvegicus 5-8 20571963-3 2010 Sulfite is a very reactive and potentially toxic molecule and has to be detoxified by the enzyme sulfite oxidase (SOX). Sulfites 0-7 sulfite oxidase Rattus norvegicus 114-117 18579106-4 2008 In the present study, sulfite toxicity towards isolated rat hepatocytes was markedly increased by partial inhibition of cytochrome a/a(3) by cyanide or by putting rats on a high-tungsten/low-molybdenum diet, which result in inactivation of sulfite oxidase. Sulfites 22-29 sulfite oxidase Rattus norvegicus 240-255 18553142-2 2009 Sulfite oxidase (SOX) is an essential enzyme in the pathway of the oxidative degradation of sulfite to sulfate protecting cells from sulfite toxicity. Sulfites 92-99 sulfite oxidase Rattus norvegicus 0-15 18553142-2 2009 Sulfite oxidase (SOX) is an essential enzyme in the pathway of the oxidative degradation of sulfite to sulfate protecting cells from sulfite toxicity. Sulfites 92-99 sulfite oxidase Rattus norvegicus 17-20 18553142-2 2009 Sulfite oxidase (SOX) is an essential enzyme in the pathway of the oxidative degradation of sulfite to sulfate protecting cells from sulfite toxicity. Sulfites 133-140 sulfite oxidase Rattus norvegicus 0-15 18553142-2 2009 Sulfite oxidase (SOX) is an essential enzyme in the pathway of the oxidative degradation of sulfite to sulfate protecting cells from sulfite toxicity. Sulfites 133-140 sulfite oxidase Rattus norvegicus 17-20 18553142-4 2009 For this purpose, rats were divided into four groups: control, sulfite-treated, SOX-deficient, and sulfite-treated SOX-deficient groups. Sulfites 99-106 sulfite oxidase Rattus norvegicus 115-118 18553142-10 2009 In conclusion, sulfite treatment affects the antioxidant/oxidant balance of the plasma cells of the rats toward oxidants in SOX-deficient groups. Sulfites 15-22 sulfite oxidase Rattus norvegicus 124-127 18842692-2 2008 Sulfite is oxidized to sulfate ion by sulfite oxidase (SOX, EC. Sulfites 0-7 sulfite oxidase Rattus norvegicus 38-53 18286237-1 2008 A noticeable effect of sulfite treatment was observed on the plasma ceruloplasmin ferroxidase activity of rats with normal sulfite oxidase activity when compared to normal controls. Sulfites 23-30 sulfite oxidase Rattus norvegicus 123-138 18286237-4 2008 Treating SOX-deficient groups with sulfite did not alter plasma level of Mn but made plasma level of Cu back to its normal level. Sulfites 35-42 sulfite oxidase Rattus norvegicus 9-12 18842692-2 2008 Sulfite is oxidized to sulfate ion by sulfite oxidase (SOX, EC. Sulfites 0-7 sulfite oxidase Rattus norvegicus 55-58 17613108-0 2007 Effect of ingested sulfite on hippocampus antioxidant enzyme activities in sulfite oxidase competent and deficient rats. Sulfites 19-26 sulfite oxidase Rattus norvegicus 75-90 17613108-2 2007 Sulfite, which is a very reactive and potentially toxic molecule, is detoxified by the enzyme sulfite oxidase (SOX). Sulfites 0-7 sulfite oxidase Rattus norvegicus 94-109 17613108-2 2007 Sulfite, which is a very reactive and potentially toxic molecule, is detoxified by the enzyme sulfite oxidase (SOX). Sulfites 0-7 sulfite oxidase Rattus norvegicus 111-114 17613108-4 2007 It has been suggested that SOX deficient rats might be used as a model for the prediction of sulfite toxicity in humans. Sulfites 93-100 sulfite oxidase Rattus norvegicus 27-30 15681120-2 2005 Sulfite is oxidized to sulfate ion by sulfite oxidase (SOX, EC. Sulfites 0-7 sulfite oxidase Rattus norvegicus 38-53 15681120-2 2005 Sulfite is oxidized to sulfate ion by sulfite oxidase (SOX, EC. Sulfites 0-7 sulfite oxidase Rattus norvegicus 55-58 15681120-8 2005 In SOX-deficient rats, TBARS levels were found to be significantly increased with sulfite exposure. Sulfites 82-89 sulfite oxidase Rattus norvegicus 3-6 15681120-9 2005 Vitamin E reversed the observed detrimental effects of sulfite in the SOX-deficient rats on their hippocampal TBARS but not on their active avoidance learning. Sulfites 55-62 sulfite oxidase Rattus norvegicus 70-73 17000536-7 2006 It was concluded that exogenous administration of sulfite affected the brain electrical activity in SOX deficiency, and improved neuroprotection. Sulfites 50-57 sulfite oxidase Rattus norvegicus 100-103 16150492-1 2006 Sulfite oxidase (SOX) is an essential enzyme in the pathway of the oxidative degradation of sulfur amino acids, and protects cells from sulfite (SO(3)(2-)) toxicity. Sulfites 136-143 sulfite oxidase Rattus norvegicus 0-15 16150492-1 2006 Sulfite oxidase (SOX) is an essential enzyme in the pathway of the oxidative degradation of sulfur amino acids, and protects cells from sulfite (SO(3)(2-)) toxicity. Sulfites 136-143 sulfite oxidase Rattus norvegicus 17-20 16150492-17 2006 Furthermore, sulfite exposure resulted in greater lipid peroxidation and more electrophysiological alterations in the SOX deficient rats than in the control rats. Sulfites 13-20 sulfite oxidase Rattus norvegicus 118-121