PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17971421-2 2008 In this study, we investigated mechanisms by which acute exposure to peroxynitrite impairs function of the sodium-dependent hemicholinium-3 (HC-3)-sensitive choline transporter (CHT) that provides substrate for acetylcholine synthesis. Hemicholinium 3 124-139 solute carrier family 6 member 8 Rattus norvegicus 157-176 17971421-2 2008 In this study, we investigated mechanisms by which acute exposure to peroxynitrite impairs function of the sodium-dependent hemicholinium-3 (HC-3)-sensitive choline transporter (CHT) that provides substrate for acetylcholine synthesis. Hemicholinium 3 124-139 solute carrier family 6 member 8 Rattus norvegicus 178-181 17971421-2 2008 In this study, we investigated mechanisms by which acute exposure to peroxynitrite impairs function of the sodium-dependent hemicholinium-3 (HC-3)-sensitive choline transporter (CHT) that provides substrate for acetylcholine synthesis. Hemicholinium 3 141-145 solute carrier family 6 member 8 Rattus norvegicus 157-176 17971421-2 2008 In this study, we investigated mechanisms by which acute exposure to peroxynitrite impairs function of the sodium-dependent hemicholinium-3 (HC-3)-sensitive choline transporter (CHT) that provides substrate for acetylcholine synthesis. Hemicholinium 3 141-145 solute carrier family 6 member 8 Rattus norvegicus 178-181 14585997-1 2003 Presynaptic synthesis of acetylcholine (ACh) requires a steady supply of choline, acquired by a plasma membrane, hemicholinium-3-sensitive (HC-3) choline transporter (CHT). Hemicholinium 3 113-128 solute carrier family 6 member 8 Rattus norvegicus 146-165 16500685-10 2006 The choline transporter inhibitor hemicholinium-3 blocked the neuroprotective effect of ALC. Hemicholinium 3 34-49 solute carrier family 6 member 8 Rattus norvegicus 4-23 16539662-3 2006 Pressure ejections of hemicholinium-3 (HC-3), a selective CHT blocker, dose-dependently reduced the uptake rate of exogenous choline as well as that of choline generated in response to terminal depolarization. Hemicholinium 3 22-37 solute carrier family 6 member 8 Rattus norvegicus 58-61 16539662-3 2006 Pressure ejections of hemicholinium-3 (HC-3), a selective CHT blocker, dose-dependently reduced the uptake rate of exogenous choline as well as that of choline generated in response to terminal depolarization. Hemicholinium 3 39-43 solute carrier family 6 member 8 Rattus norvegicus 58-61 8467907-2 1993 Choline transporter activity was titrated with hemicholinium-3, a known competitive inhibitor of the transporter. Hemicholinium 3 47-62 solute carrier family 6 member 8 Rattus norvegicus 0-19 8937895-3 1996 High-affinity choline uptake (HACU, the rate-limiting step in acetlcholine synthesis) and binding to [3H]-hemicholinium-3 (HC-3, a specific ligand for the choline transporter) were chosen as indicators of acetylcholine synthesis. Hemicholinium 3 123-127 solute carrier family 6 member 8 Rattus norvegicus 155-174 7896942-1 1995 A putative choline transporter (CHOT1) has been cloned from rat brain and is reported to express a high-affinity, sodium-dependent, hemicholinium-3-insensitive choline transporter in oocytes. Hemicholinium 3 132-145 solute carrier family 6 member 8 Rattus norvegicus 11-30 7896942-1 1995 A putative choline transporter (CHOT1) has been cloned from rat brain and is reported to express a high-affinity, sodium-dependent, hemicholinium-3-insensitive choline transporter in oocytes. Hemicholinium 3 132-145 solute carrier family 6 member 8 Rattus norvegicus 32-37