PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25293641-5	2015	The ADA-catalyzed conversion of adenosine to inosine and ammonia leads to a local pH alteration, changing the absorbance maximum of PR (from 425 to 567 nm), which is measured optically.	Ammonia	57-64	adenosine deaminase	Homo sapiens	4-7	
27591790-2	2016	ADA converts adenosine to inosine and liberates ammonia.	Ammonia	48-55	adenosine deaminase	Homo sapiens	0-3	
25580842-4	2015	The ADA catalyzes the cleavage of adenosine to inosine and NH3 , the latter can be accurately determined by indophenol method.	Ammonia	59-62	adenosine deaminase	Homo sapiens	4-7	
20399005-3	2010	ADA activity in the CSF was calculated based on ammonia liberated from adenosine and quantified spectrophotometrically.	Ammonia	48-55	adenosine deaminase	Homo sapiens	0-3	
23389721-0	2013	High pleural ammonia negatively interferes with the measurement of adenosine deaminase activity.	Ammonia	13-20	adenosine deaminase	Homo sapiens	67-86	
12552246-6	2003	The activity of adenosine deaminase in the mucosal homogenates was measured by determination of ammonia liberated from the substrate and expressed in nmol NH3/mg protein/min.	Ammonia	96-103	adenosine deaminase	Homo sapiens	16-35	
18608782-2	2009	Adenosine deaminase (ADA), an enzyme involved in purine metabolism, catalyzes the hydrolytic breakdown of adenosine into inosine and free ammonia.	Ammonia	138-145	adenosine deaminase	Homo sapiens	0-19	
18608782-2	2009	Adenosine deaminase (ADA), an enzyme involved in purine metabolism, catalyzes the hydrolytic breakdown of adenosine into inosine and free ammonia.	Ammonia	138-145	adenosine deaminase	Homo sapiens	21-24	
12552246-6	2003	The activity of adenosine deaminase in the mucosal homogenates was measured by determination of ammonia liberated from the substrate and expressed in nmol NH3/mg protein/min.	Ammonia	155-158	adenosine deaminase	Homo sapiens	16-35	
3039004-3	1987	Enzyme activity is determined by colorimetric estimation of NH3 released from adenosine, the product of 5"-nucleotidase activity in the presence of adenosine deaminase.	Ammonia	60-63	adenosine deaminase	Homo sapiens	148-167	
34851227-1	2021	Adenosine deaminase is a zinc+2 dependent key enzyme of purine metabolism which irreversibly converts adenosine to inosine and form ammonia.	Ammonia	132-139	adenosine deaminase	Homo sapiens	0-19	
2788175-4	1989	We investigated whether the deamination of adenosine by adenosine deaminase in hematopoietic cells might liberate sufficient ammonia to form amidated C3 and thereby trigger complement-mediated inflammation at ischemic sites.	Ammonia	125-132	adenosine deaminase	Homo sapiens	56-75	
2788175-7	1989	NH3 production derived only from the deamination of adenosine by the enzyme adenosine deaminase and was abolished by 0.4 microM 2"-deoxycoformycin, a specific inhibitor of adenosine deaminase.	Ammonia	0-3	adenosine deaminase	Homo sapiens	76-95	
2788175-7	1989	NH3 production derived only from the deamination of adenosine by the enzyme adenosine deaminase and was abolished by 0.4 microM 2"-deoxycoformycin, a specific inhibitor of adenosine deaminase.	Ammonia	0-3	adenosine deaminase	Homo sapiens	172-191	
7670131-3	1995	Adenosine deaminase activity was measured in mucosa homogenates by determination of ammonia liberated from substrate.	Ammonia	84-91	adenosine deaminase	Homo sapiens	0-19	
1510925-1	1992	Nebularine undergoes hydration at the active site of adenosine deaminase, in a reaction analogous to a partial reaction in the displacement of ammonia from adenosine by water, to generate an inhibitory complex that captures much of the binding affinity expected of an ideal transition-state analogue.	Ammonia	143-150	adenosine deaminase	Homo sapiens	53-72	
2373272-3	1990	The activity of ADA in mucosal homogenates was measured by determination of the ammonia liberated from the substrate.	Ammonia	80-87	adenosine deaminase	Homo sapiens	16-19	
835828-0	1977	Automated adenosine deaminase enzyme determination with an ammonia-sensing membrand electrode.	Ammonia	59-66	adenosine deaminase	Homo sapiens	10-29	
4067516-2	1985	For the continuous determination of adenosine deaminase, the liberated ammonia is estimated by coupling the liberated NH3 with 2-oxoglutarate.	Ammonia	71-78	adenosine deaminase	Homo sapiens	36-55	
4067516-2	1985	For the continuous determination of adenosine deaminase, the liberated ammonia is estimated by coupling the liberated NH3 with 2-oxoglutarate.	Ammonia	118-121	adenosine deaminase	Homo sapiens	36-55	
3837376-0	1985	[Study on the activity of adenosine deaminase in blood by an ammonia gas-sensing electrode].	Ammonia	61-68	adenosine deaminase	Homo sapiens	26-45	
598590-0	1977	Detection of ammonia-producing enzymes after electrophoresis: a screening procedure for adenosine deaminase in blood [proceedings].	Ammonia	13-20	adenosine deaminase	Homo sapiens	88-107	
4106191-1	1971	The hydrolysis of adenosine 3"-monophosphate by serum acid phosphatase has been coupled to the liberation of ammonia from the adenosine generated through the action of exogenous adenosine deaminase.	Ammonia	109-116	adenosine deaminase	Homo sapiens	178-197