PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10224667-1 1999 Glutaminase is the enzyme which hydrolyses glutamine, the main respiratory fuel of the intestine, to yield glutamate and ammonia. Ammonia 121-128 glutaminase Homo sapiens 0-11 14276160-1 1965 In four persons of one family the existence of an enzymatic defect, presumably consisting of a deficiency of glutaminase in the cells of the renal tubules, is postulated, and is implied by a reduced elimination of ammonia in the urine, by a relatively low urinary pH, and by its increased titratable acidity. Ammonia 214-221 glutaminase Homo sapiens 109-120 8192245-2 1994 Therefore, we investigated the expression of the amino acid- and ammonia-metabolizing enzymes glutaminase, glutamate dehydrogenase, glutamine synthase, carbamoylphosphate synthase, and arginase immunohistochemically in a graded series of human embryos and fetuses. Ammonia 65-72 glutaminase Homo sapiens 94-130 14806390-0 1951 Role of glutaminase in the production of urinary ammonia. Ammonia 49-56 glutaminase Homo sapiens 8-19 25426679-4 2015 Kidney type glutaminase (GLS1), which is responsible for the conversion of glutamine to glutamate, produces ammonia as part of its catalytic activities and has been shown to modulate cellular acidity. Ammonia 108-115 glutaminase Homo sapiens 25-29 25529918-2 2015 Glutaminase (GA, EC 3.5.1.2) metabolizes Gln to Glu and ammonia. Ammonia 56-63 glutaminase Homo sapiens 0-11 25529918-2 2015 Glutaminase (GA, EC 3.5.1.2) metabolizes Gln to Glu and ammonia. Ammonia 56-63 glutaminase Homo sapiens 13-15 30910998-5 2019 Glutaminolysis initiates with deamination of glutamine by glutaminase (GLS), by which yields glutamate and ammonia in mitochondria. Ammonia 107-114 glutaminase Homo sapiens 58-69 30910998-5 2019 Glutaminolysis initiates with deamination of glutamine by glutaminase (GLS), by which yields glutamate and ammonia in mitochondria. Ammonia 107-114 glutaminase Homo sapiens 71-74 30646605-5 2019 Interestingly, GLS-silenced cells reproduce the effect of metformin treatment showing reduced MAP1LC3B-II and GABARAP as well as ammonia accumulation. Ammonia 129-136 glutaminase Homo sapiens 15-18 31014748-2 2019 Ammonia detoxification in hepatic encephalopathy is regulated by two enzymes: glutaminase or glutamine synthetase. Ammonia 0-7 glutaminase Homo sapiens 78-89 31014748-3 2019 The first produces ammonia and the second detoxifies the ammonia, which is why treatments are aimed at glutaminase inhibition or glutamine synthetase activation. Ammonia 19-26 glutaminase Homo sapiens 103-114 31014748-3 2019 The first produces ammonia and the second detoxifies the ammonia, which is why treatments are aimed at glutaminase inhibition or glutamine synthetase activation. Ammonia 57-64 glutaminase Homo sapiens 103-114 30144404-1 2018 Glutaminase-1 (GLS1) is a mitochondrial enzyme found in endothelial cells (ECs) that metabolizes glutamine to glutamate and ammonia. Ammonia 124-131 glutaminase Homo sapiens 0-13 30144404-1 2018 Glutaminase-1 (GLS1) is a mitochondrial enzyme found in endothelial cells (ECs) that metabolizes glutamine to glutamate and ammonia. Ammonia 124-131 glutaminase Homo sapiens 15-19 29441491-0 2018 In Silico Preliminary Association of Ammonia Metabolism Genes GLS, CPS1, and GLUL with Risk of Alzheimer"s Disease, Major Depressive Disorder, and Type 2 Diabetes. Ammonia 37-44 glutaminase Homo sapiens 62-65 28871132-6 2017 We apply this assay to quantitatively measure glutamine-derived ammonia in lung cancer cell lines with differential expression of glutaminase. Ammonia 64-71 glutaminase Homo sapiens 130-141 22049910-1 2011 Glutaminase (GLS1/2) catalyzes the conversion of L-glutamine to L-glutamate and ammonia. Ammonia 80-87 glutaminase Homo sapiens 13-19 23149879-3 2013 The products of GA reaction, glutamate and ammonia, are essential metabolites for energy and biosynthetic purposes but they are also hazardous compounds at concentrations beyond their normal physiological thresholds. Ammonia 43-50 glutaminase Homo sapiens 16-18 20673233-5 2011 The present review focuses upon interorgan ammonia metabolism in health and disease describing the role of the key enzymes, glutamine synthase and glutaminase. Ammonia 43-50 glutaminase Homo sapiens 147-158 16716587-0 2007 Physico-chemical method for ammonia removal from synthetic wastewater using limestone and GAC in batch and column studies. Ammonia 28-35 glutaminase Homo sapiens 90-93