PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25700560-4	2015	Our results show that ammonia production increased in SIRT5-silenced and decreased in SIRT5-overexpressing cells.	Ammonia	22-29	sirtuin 5	Homo sapiens	54-59	
26867736-3	2016	Recent studies demonstrated that Lys succinylation and Sirt5 are involved in diverse cellular metabolic processes including urea cycle, ammonia transfer, and glucose metabolism.	Ammonia	136-143	sirtuin 5	Homo sapiens	55-60	
25700560-0	2015	SIRT5 regulation of ammonia-induced autophagy and mitophagy.	Ammonia	20-27	sirtuin 5	Homo sapiens	0-5	
25700560-1	2015	In liver the mitochondrial sirtuin, SIRT5, controls ammonia detoxification by regulating CPS1, the first enzyme of the urea cycle.	Ammonia	52-59	sirtuin 5	Homo sapiens	36-41	
25700560-3	2015	To address the possibility that SIRT5 is involved in ammonia production also in nonliver cells, clones of human breast cancer cell lines MDA-MB-231 and mouse myoblast C2C12, overexpressing or silenced for SIRT5 were produced.	Ammonia	53-60	sirtuin 5	Homo sapiens	32-37	
25700560-4	2015	Our results show that ammonia production increased in SIRT5-silenced and decreased in SIRT5-overexpressing cells.	Ammonia	22-29	sirtuin 5	Homo sapiens	86-91	
25700560-5	2015	We also obtained the same ammonia increase when using a new specific inhibitor of SIRT5 called MC3482.	Ammonia	26-33	sirtuin 5	Homo sapiens	82-87	
25700560-6	2015	SIRT5 regulates ammonia production by controlling glutamine metabolism.	Ammonia	16-23	sirtuin 5	Homo sapiens	0-5	
25700560-12	2015	In conclusion we propose that the role of SIRT5 in nonliver cells is to regulate ammonia production and ammonia-induced autophagy by regulating glutamine metabolism.	Ammonia	81-88	sirtuin 5	Homo sapiens	42-47	
25700560-12	2015	In conclusion we propose that the role of SIRT5 in nonliver cells is to regulate ammonia production and ammonia-induced autophagy by regulating glutamine metabolism.	Ammonia	104-111	sirtuin 5	Homo sapiens	42-47