PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26880641-5	2016	Both DMGDH and SDH contain FAD and both have tightly bound tetrahydrofolate (THF), a folate coenzyme.	5,6,7,8-tetrahydrofolic acid	59-75	sarcosine dehydrogenase	Homo sapiens	15-18	
21510664-4	2011	This reaction is similar to the previously described demethylation reactions conducted by the enzymes dimethylglycine dehydrogenase and sarcosine dehydrogenase, in which protein-bound tetrahydrofolate serves as an accepter of the formaldehyde that is generated.	5,6,7,8-tetrahydrofolic acid	184-200	sarcosine dehydrogenase	Homo sapiens	118-159	
26880641-16	2016	Our hypotheses are that THF is bound to native LSD1 by analogy to DMGDH and SDH and that the bound THF serves to protect the FAD class of histone demethylases from the destructive effects of formaldehyde generation by formation of 5,10-methylene-THF.	5,6,7,8-tetrahydrofolic acid	24-27	sarcosine dehydrogenase	Homo sapiens	76-79	
3427080-10	1987	The existence of a catalytically significant binding site for tetrahydrofolate appears to be a general property of sarcosine oxidizing enzymes since similar results have previously been obtained with mammalian sarcosine dehydrogenase, an enzyme that is structurally and mechanistically very different from bacterial sarcosine oxidase.	5,6,7,8-tetrahydrofolic acid	62-78	sarcosine dehydrogenase	Homo sapiens	210-233	
26880641-5	2016	Both DMGDH and SDH contain FAD and both have tightly bound tetrahydrofolate (THF), a folate coenzyme.	5,6,7,8-tetrahydrofolic acid	77-80	sarcosine dehydrogenase	Homo sapiens	15-18	
24715612-4	2014	This reaction is similar to those performed by dimethylglycine dehydrogenase and sarcosine dehydrogenase, in which protein-bound tetrahydrofolate (THF) was proposed to serve as an acceptor of the generated formaldehyde.	5,6,7,8-tetrahydrofolic acid	129-145	sarcosine dehydrogenase	Homo sapiens	81-104	
24715612-4	2014	This reaction is similar to those performed by dimethylglycine dehydrogenase and sarcosine dehydrogenase, in which protein-bound tetrahydrofolate (THF) was proposed to serve as an acceptor of the generated formaldehyde.	5,6,7,8-tetrahydrofolic acid	147-150	sarcosine dehydrogenase	Homo sapiens	81-104