PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10658532-1 1999 Our early reports have indicated that vitamin K3 (VK3) exerts antitumour activity by inhibiting Cdk1 activity and overexpressing the c-myc gene to induce an apoptotic cell death. Vitamin K 3 38-48 cyclin dependent kinase 1 Homo sapiens 96-100 33982750-6 2021 Increased CDK1 expression was confirmed in HNSCC cells, and menadione, the top predicted potential drug, exerted significant inhibitory effects against HNSCC cell proliferation and markedly reversed CDK1 expression. Vitamin K 3 60-69 cyclin dependent kinase 1 Homo sapiens 199-203 8382492-0 1993 Vitamin K3 inhibits growth of human hepatoma HepG2 cells by decreasing activities of both p34cdc2 kinase and phosphatase. Vitamin K 3 0-10 cyclin dependent kinase 1 Homo sapiens 90-97 8382492-6 1993 Our results suggest that vitamin K3 inhibits the growth of HepG2 cells via a cell cycle progression delay and altered phosphorylation patterns and activities of both p34cdc2 kinase and protein-tyrosine phosphatase. Vitamin K 3 25-35 cyclin dependent kinase 1 Homo sapiens 166-173