PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11053775-5 2000 The results show that H(2)O(2)-induced increases in egr-1, fra-1, and c-jun mRNA levels, as measured by Northern blot analysis, are time and dose dependent with the peak of the response within 2 h. Tyrosine kinase inhibitors (genistein, amino-genistein, and tyrphostin 51) significantly attenuated H(2)O(2)-induced expression of these genes and a tyrosine phosphatase inhibitor (perox-vanadate) stimulated their expression. 4'-amino-6-hydroxyflavone 237-252 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens 70-75