PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15615541-4 2004 Accordingly, we investigated the JNK-inhibiting properties of a number of variants of the right-hand moiety of the molecule, which led to the identification of 2-(benzoylaminomethyl)thiophene sulfonamide benzotriazole (AS600292, compound 50a), the first potent and selective JNK inhibitor of this class which demonstrates a protective action against neuronal cell death induced by growth factor and serum deprivation. 2-(benzoylaminomethyl)thiophene sulfonamide benzotriazole 160-217 mitogen-activated protein kinase 8 Homo sapiens 33-36 15615541-4 2004 Accordingly, we investigated the JNK-inhibiting properties of a number of variants of the right-hand moiety of the molecule, which led to the identification of 2-(benzoylaminomethyl)thiophene sulfonamide benzotriazole (AS600292, compound 50a), the first potent and selective JNK inhibitor of this class which demonstrates a protective action against neuronal cell death induced by growth factor and serum deprivation. 2-(benzoylaminomethyl)thiophene sulfonamide benzotriazole 160-217 mitogen-activated protein kinase 8 Homo sapiens 275-278