PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30481027-4 2018 Among these analogues, 15n with tetrazole in place of 1,2,4-triazole exhibited optimal inhibition of human umbilical vein endothelial cell proliferation with an IC50 of 73 nM without a significant effect on CYP3A4 (EC50 > 20 muM). 15n 23-26 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 207-213 17985934-5 2007 The growth protocol yields approximately 2.5 mg of the enzymatically active, uniformly 13C,15N-enriched CYP3A4 from 1 L of growth medium. 15n 91-94 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 104-110 17495418-0 2007 Effect of ion suppression on judgment of enzyme inhibition and avoidance of error by utilizing a stable isotope-labeled probe substrate: example of CYP3A4 inhibition with [13C4,15N] labeled midazolam as a substrate. 15n 177-180 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 148-154