PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12421568-1	2002	Interleukin-1 (IL-1) is a multifunctional cytokine known to act as a growth factor for AIDS-KS cells.	Potassium	92-94	interleukin 1 alpha	Homo sapiens	0-13	
12421568-1	2002	Interleukin-1 (IL-1) is a multifunctional cytokine known to act as a growth factor for AIDS-KS cells.	Potassium	92-94	interleukin 1 alpha	Homo sapiens	15-19	
12421568-2	2002	In addition to its mitogenic effects, we found that IL-1 induced the protection of KS cells from apoptotic death induced by serum deprivation in a dose-dependent manner.	Potassium	83-85	interleukin 1 alpha	Homo sapiens	52-56	
12421568-3	2002	AIDS-KS cells as well as cells derived from iatrogenic and sporadic KS exhibited a similar response to IL-1, which stresses the key role of this cytokine in the pathogenesis of KS regardless of its epidemiological form.	Potassium	5-7	interleukin 1 alpha	Homo sapiens	103-107	
12421568-5	2002	The effects of IL-1 were inhibited by IL-1ra, suggesting that imbalance between these two counter-acting cytokines may contribute to the altered accumulation of KS spindle cells.	Potassium	161-163	interleukin 1 alpha	Homo sapiens	15-19	
34052311-7	2021	In potassium-free buffer, LDL(-)-induced IL-1beta reached a level similar to that induced by cotreatment with LDL(-) and PA-BSA.	Potassium	3-12	interleukin 1 alpha	Homo sapiens	41-49	
34664888-2	2021	Systemic pro-inflammatory cytokines released from synovial tissues in rheumatoid arthritis, such as interleukin (IL)-1beta, IL-6, and tumor necrosis factor-alpha, could have direct effects on cardiac electrophysiology, particularly changes in the expression and function of potassium and calcium channels, resulting in QT interval prolongation on surface electrocardiogram (ECG) and an increased predisposition to develop lethal ventricular arrhythmias.	Potassium	274-283	interleukin 1 alpha	Homo sapiens	100-122	
35254168-9	2022	Moreover, SVA 3D induces calcium influx and potassium efflux, which triggers IL-1beta secretion.	Potassium	44-53	interleukin 1 alpha	Homo sapiens	77-85	
30138927-10	2018	RESULTS: Elevated extracellular potassium prevented the priming factor IL-1alpha from inducing the production of reactive oxygen species (ROS).	Potassium	32-41	interleukin 1 alpha	Homo sapiens	71-80	
31998284-6	2019	Furthermore, LPC induced pyroptosis in both cells and the activation of the inflammasome with IL-1beta secretion, which was dependent on potassium efflux and lysosomal damage in human monocytes.	Potassium	137-146	interleukin 1 alpha	Homo sapiens	94-102	
30485804-3	2018	Furthermore, BAX/BAK signaling induces a parallel pathway to NLRP3 inflammasome-mediated caspase-1-dependent IL-1beta maturation that requires potassium efflux.	Potassium	143-152	interleukin 1 alpha	Homo sapiens	109-117	
33718825-5	2021	Using genetic and pharmacological inhibition, we show that the induction of mature IL-1beta is through a non-classical pathway dependent upon caspase-1, caspase-8, the NLRP3 inflammasome, potassium efflux, and autophagy while being independent of TRIF (TICAM1), vitamin D3, and pyroptosis.	Potassium	188-197	interleukin 1 alpha	Homo sapiens	83-91	
32582195-6	2020	A mechanistic study revealed that S. sonnei induced IL-1beta production through P2X7 receptor-mediated potassium efflux, reactive oxygen species generation, lysosomal acidification, and mitochondrial damage.	Potassium	103-112	interleukin 1 alpha	Homo sapiens	52-60	
32010303-13	2020	Furthermore, a high concentration of potassium ions significantly reduced the secretion of IL-1beta after induction/stimulation.	Potassium	37-46	interleukin 1 alpha	Homo sapiens	91-99