PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17191919-8 2005 One product, indirubin 5,5"-dicarboxylic acid 5-methyl ester, inhibited GSK-3alpha/beta with an IC50 of 14 nM and selectivity nearly 40-fold over CDK1 and CDK5. indirubin 5,5"-dicarboxylic acid 5-methyl ester 13-60 cyclin dependent kinase 1 Homo sapiens 146-150