PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33195255-1	2020	The primary role of apurinic/apyrimidinic (AP) endonuclease APE1 in human cells is the cleavage of the sugar phosphate backbone 5" to an AP site in DNA to produce a single-strand break with a 5"-deoxyribose phosphate and 3"-hydroxyl end groups.	Sugar Phosphates	103-118	apurinic/apyrimidinic endodeoxyribonuclease 1	Homo sapiens	60-64	
9614142-2	1998	DNA polymerase beta (beta-pol) cleaves the sugar-phosphate bond 3" to an intact apurinic/apyrimidinic (AP) site (i.e. AP lyase activity).	Sugar Phosphates	43-58	apurinic/apyrimidinic endodeoxyribonuclease 1	Homo sapiens	118-126	
27063150-5	2016	It was also shown that Cu(2+) ions abrogated the DNA binding ability of APE1, possibly, due to a strong interaction with DNA bases and the sugar-phosphate backbone.	Sugar Phosphates	139-154	apurinic/apyrimidinic endodeoxyribonuclease 1	Homo sapiens	72-76	
11677229-6	2002	This domain is known to bind single-stranded DNA, provide 5"-phosphate recognition of gapped DNA, and cleave the sugar-phosphate bond 3" to an intact apurinic/apyrimidinic (AP) site (i.e. AP lyase activity) including 5"-deoxyribose phosphate lyase activity.	Sugar Phosphates	113-128	apurinic/apyrimidinic endodeoxyribonuclease 1	Homo sapiens	188-196	
11554316-3	2001	Subsequently, an AP endonuclease or AP lyase activity incises the abasic site, followed by short-patch gap-filling, excision of the base-free sugar-phosphate residue, and ligation.	Sugar Phosphates	142-157	apurinic/apyrimidinic endodeoxyribonuclease 1	Homo sapiens	36-44	
10667800-2	2000	The biologically critical human base excision repair enzyme APE1 cleaves the DNA sugar-phosphate backbone at a position 5" of AP sites to prime DNA repair synthesis.	Sugar Phosphates	81-96	apurinic/apyrimidinic endodeoxyribonuclease 1	Homo sapiens	60-64