PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27441453-6	2016	Using menadione as the redox-cycling chemical, we discovered that this enzymatic reaction blocks metabolic activation of parathion in rat and human liver microsomes and in recombinant CYPs important to parathion metabolism, including CYP1A2, CYP2B6, and CYP3A4.	Parathion	121-130	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	242-248	
21514354-9	2011	Changes in hepatic CYP2B6 and CYP2C19 content had more of an influence on cholinesterase inhibition for exposures to chlorpyrifos than parathion, which agrees with previously reported literature that these CYPs are more reaction biased for desulfurization (activation) and dearylation (detoxification) of chlorpyrifos compared to parathion.	Parathion	135-144	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	19-25	
21514354-2	2011	Phosphororthioate OPs like chlorpyrifos and parathion are directly activated and detoxified by various cytochrome P450s (CYPs), with the primary CYPs involved being CYP2B6 and CYP2C19.	Parathion	44-53	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	165-171	
21514354-9	2011	Changes in hepatic CYP2B6 and CYP2C19 content had more of an influence on cholinesterase inhibition for exposures to chlorpyrifos than parathion, which agrees with previously reported literature that these CYPs are more reaction biased for desulfurization (activation) and dearylation (detoxification) of chlorpyrifos compared to parathion.	Parathion	330-339	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	19-25	
17079358-0	2007	Human hepatic cytochrome p450-specific metabolism of parathion and chlorpyrifos.	Parathion	53-62	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	25-29