PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2412971-11 1985 A metabolite of adenine which could contribute to its immunosuppressive activity may be 2-hydroxyadenine since it is derived from the xanthine oxidase catalysed oxidation of adenine inhibited hypoxanthine-guanine phosphoribosyltransferase gave similar renal toxicity to adenine and was immunosuppressive. isoguanine 88-104 hypoxanthine guanine phosphoribosyl transferase Mus musculus 192-238