PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3899841-5 1985 Using Cox multiple regression analysis and adjusting for slight imbalance between the two treatment groups, the therapeutic effect of azathioprine was statistically significant (p = 0.01), with azathioprine reducing the risk of dying to 59% of that observed during placebo treatment (95% confidence interval 40%-90%) or improving survival time by 20 mo in the average patient. Azathioprine 134-146 cytochrome c oxidase subunit 8A Homo sapiens 6-9 3899841-5 1985 Using Cox multiple regression analysis and adjusting for slight imbalance between the two treatment groups, the therapeutic effect of azathioprine was statistically significant (p = 0.01), with azathioprine reducing the risk of dying to 59% of that observed during placebo treatment (95% confidence interval 40%-90%) or improving survival time by 20 mo in the average patient. Azathioprine 194-206 cytochrome c oxidase subunit 8A Homo sapiens 6-9 22450143-9 2012 Early azathioprine use was significantly associated with the time to intestinal surgery in Crohn"s disease patients; in a multivariate Cox analysis (HR: 0.43, 95% confidence interval (CI): 0.28-0.65) and after matching on propensity scores for azathioprine use (HR: 0.42,95% CI:0.26-0.67). Azathioprine 6-18 cytochrome c oxidase subunit 8A Homo sapiens 135-138 22233693-11 2012 Early AZA use was significantly associated with the time to intestinal surgery in CD patients; in a multivariate Cox analysis (HR: 0.43, 95% confidence interval (CI): 0.28-0.65) and after matching on propensity scores for AZA use (HR: 0.42, 95% CI: 0.26-0.67). Azathioprine 6-9 cytochrome c oxidase subunit 8A Homo sapiens 113-116 18692056-8 2008 Multivariate Cox models showed that both structuring behavior at diagnosis (hazard ratio [HR], 2.54; 95% confidence interval [CI]: 1.58-4.01) and treatment with corticosteroids (HR, 2.98; 95% CI: 1.64-5.41) were associated with increased risk for surgery, whereas treatment with azathioprine (HR, 0.51; 95% CI: 0.33-0.78) was associated with decreased risk. Azathioprine 279-291 cytochrome c oxidase subunit 8A Homo sapiens 13-16 2672226-1 1989 We describe a bootstrap investigation of the stability of a Cox proportional hazards regression model resulting from the analysis of a clinical trial of azathioprine versus placebo in patients with primary biliary cirrhosis. Azathioprine 153-165 cytochrome c oxidase subunit 8A Homo sapiens 60-63