PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25804610-5 2015 Pharmacologic Nrf2 activation by topical biweekly applications of small (40 nmol) quantities of the potent bis(cyano enone) inducer TBE-31 has a similar protective effect against solar-simulated UV radiation in animals receiving long-term treatment with the immunosuppressive agent azathioprine. Azathioprine 282-294 NFE2 like bZIP transcription factor 2 Homo sapiens 14-18 21803983-0 2011 Oral azathioprine leads to higher incorporation of 6-thioguanine in DNA of skin than liver: the protective role of the Keap1/Nrf2/ARE pathway. Azathioprine 5-17 NFE2 like bZIP transcription factor 2 Homo sapiens 125-129 21803983-6 2011 Genetic upregulation of the Keap1/Nrf2/ARE pathway, a major cellular regulator of the expression of a network of cytoprotective genes, reduces the incorporation of 6-thioguanine in DNA of both skin and liver following treatment with azathioprine. Azathioprine 233-245 NFE2 like bZIP transcription factor 2 Homo sapiens 34-38 21803983-9 2011 Our findings suggest that activation of the Keap1/Nrf2/ARE pathway could reduce the risk for skin cancer in patients receiving long-term azathioprine therapy. Azathioprine 137-149 NFE2 like bZIP transcription factor 2 Homo sapiens 50-54 35052616-1 2022 Hybrids based on an aza-analogue of CGP37157, a mitochondrial Na+/Ca2+ exchanger antagonist, and lipoic acid were obtained in order to combine in a single molecule the antioxidant and NRF2 induction properties of lipoic acid and the neuroprotective activity of CGP37157. Azathioprine 20-23 NFE2 like bZIP transcription factor 2 Homo sapiens 184-188 33882797-3 2021 This study aimed to evaluate the gene expression of sod1, sod2, cat, nrf2 and gp91phox in CD patients before and after Azathioprine (Aza) consumption. Azathioprine 119-131 NFE2 like bZIP transcription factor 2 Homo sapiens 69-73 33882797-3 2021 This study aimed to evaluate the gene expression of sod1, sod2, cat, nrf2 and gp91phox in CD patients before and after Azathioprine (Aza) consumption. Azathioprine 133-136 NFE2 like bZIP transcription factor 2 Homo sapiens 69-73 33882797-7 2021 Following treatment with Aza, the decreased expression levels of gp91phox (P-value < 0.05), cat (P-value < 0.05), sod1(P-value < 0.001) and nrf2 (P-value < 0.001) were observed in CD patients. Azathioprine 25-28 NFE2 like bZIP transcription factor 2 Homo sapiens 140-144