PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16087337-1 2005 The 2-arylvinyl moiety in 1-(3-chlorophenyl)-3-(4-piperidyl)-5-[(E)-2-(5-chloro-1H-indol-3-yl)vinyl]pyrazole 2, which has previously shown improved DNA gyrase inhibition and target-related antibacterial activity, was transformed to other groups and the in vitro antibacterial activity of the synthesized compounds was evaluated. 2-arylvinyl 4-15 DNA topoisomerase II alpha Homo sapiens 148-158