PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19105274-1	2008	OBJECTIVE: To investigate the effect of rhizoma paridis total saponins(RPTS)on the levels of tumor necrosis factor alpha (TNF-alpha), interleukin-1 beta (IL-1 beta) and interleukin-6 (IL-6) in blood serum of two-hit rat model induced by multiple fractures and lipopolysaccharide.	Saponins	62-70	tumor necrosis factor	Rattus norvegicus	93-120	
26762065-8	2015	RESULTS: Total saponins of Panacis Majoris Rhizoma might significantly decrease the levels of serum TNF-alpha, IL-1beta, IL-6 and IL-8; decrease myocardial hypertrophy indexes, myocardial infarct size, degree of ventricular dilatation and myocardial interstitial collagen volume fraction; improve heart tissue morphology and cardiac function; downregulate protein expression of pIkappaB-alpha and NF-kappaBp65; and upregulate protein expression of SIRT1.	Saponins	15-23	tumor necrosis factor	Rattus norvegicus	100-109	
20518313-0	2010	[Effects of Panax notoginseng saponins on ACE2 and TNF-alpha in rats with post-myocardial infarction-ventricular remodeling].	Saponins	30-38	tumor necrosis factor	Rattus norvegicus	51-60	
20518313-1	2010	OBJECTIVE: To research the effects of Panax notoginseng saponins (PNS) on angiotensin-converting enzymes 2 ( ACE2) and tumor necrosis factor-alpha (TNF-alpha) in rats with post-myocardial infarction ventricular remodeling.	Saponins	56-64	tumor necrosis factor	Rattus norvegicus	148-157	
18786325-10	2008	In the in vitro experiment, it was shown that rhizoma paridis total saponins in concentrations of 5, 10, 20 and 40 mg/L could inhibit remarkably the release of TNF-alpha and IL-1 beta from LPS-stimulated PMPhi of rats (all P < 0.01).	Saponins	68-76	tumor necrosis factor	Rattus norvegicus	160-169