PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2654305-5	1989	These results indicate that the systemic absorption of 1% insulin through the eyes can be enhanced at least 7-fold when 1% of the surfactant, saponin, was added to the solution.	Saponins	142-149	insulin	Homo sapiens	58-65	
7877136-7	1994	The antibody 960 also specifically increased insulin binding to intact, saponin-permeabilized IM-9 cell membranes.	Saponins	72-79	insulin	Homo sapiens	45-52	
2268285-5	1990	In 45Ca2(+)-release studies it was shown that, in saponin-permeabilized insulin-exposed cells, preincubation with exogenous PGE2 or 8-bromo cyclic AMP decreased the sensitivity of 45Ca2+ release in response to Ins(1,4,5)P3, as demonstrated by an increase in the EC50 (concn.	Saponins	50-57	insulin	Homo sapiens	72-79	
2654305-7	1989	Most importantly, the blood glucose was reduced concomitantly with the increase of blood insulin when 50 microliters of 1% insulin in 1% saponin solution was instilled in the eyes.	Saponins	137-144	insulin	Homo sapiens	89-96	
2654305-9	1989	In normal animals, 25 microliters of 1% insulin in 1% saponin reduced blood glucose from 102 mg % to 50 mg % in an hour and blood glucose remained low for at least 3 hrs.	Saponins	54-61	insulin	Homo sapiens	40-47	
2654305-10	1989	These results indicate that insulin can be delivered systemically through the eyes, particularly with the surfactant enhancers, such as saponin.	Saponins	136-143	insulin	Homo sapiens	28-35	
18198636-0	2007	[Effect of panax quinquefolius saponin on insulin sensitivity in patients of coronary heart disease with blood glucose abnormality].	Saponins	31-38	insulin	Homo sapiens	42-49	
23725454-7	2013	Additional screening using sets of saponin- and triazine-based compounds was undertaken to further validate this assay, which led to the discovery of triazine PP-II-A03 as a novel insulin mimetic.	Saponins	35-42	insulin	Homo sapiens	180-187	
18198636-1	2007	OBJECTIVE: To investigate the effect of panax quinquefolius saponin(PQS) on blood glucose, blood lipid and insulin sensitivity in patients of coronary heart disease (CHD) with blood glucose abnormality (BGA).	Saponins	60-67	insulin	Homo sapiens	107-114	
17076642-0	2006	Isolation, characterization and study of enhancing effects on nasal absorption of insulin in rat of the total saponin from Acanthophyllum squarrosum.	Saponins	110-117	insulin	Homo sapiens	82-89