PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18547688-0	2008	A promising balanced Th1 and Th2 directing immunological adjuvant, saponins from the root of Platycodon grandiflorum.	Saponins	67-75	negative elongation factor complex member C/D, Th1l	Mus musculus	21-24	
16637684-0	2006	Quillaja saponin can modulate ovalbumin-induced IgE allergic responses through regulation of Th1/Th2 balance in a murine model.	Saponins	9-16	negative elongation factor complex member C/D, Th1l	Mus musculus	93-96	
16637684-3	2006	The purpose of this study is to investigate whether Quillaja saponin can suppress ovalbumin (OVA)-induced IgE-mediated allergic responses through promoting a dominant Th1 immune response.	Saponins	61-68	negative elongation factor complex member C/D, Th1l	Mus musculus	167-170	
11999345-0	2002	Modulation of the Th1/Th2 bias by lipopeptide and saponin adjuvants in orally immunized mice.	Saponins	50-57	negative elongation factor complex member C/D, Th1l	Mus musculus	18-21	
11999345-7	2002	Our data suggest that both adjuvants enhance the mucosal as well as the systemic immune response; P3CSK4 predominantly elicits the activation of the Th1 subset, whereas saponin activates both the Th1 and Th2 subser.	Saponins	169-176	negative elongation factor complex member C/D, Th1l	Mus musculus	196-199	
32012760-0	2020	Mechanisms of Mixed Th1/Th2 Responses in Mice Induced by Albizia julibrissin Saponin Active Fraction by in Silico Analysis.	Saponins	77-84	negative elongation factor complex member C/D, Th1l	Mus musculus	20-23	
32012760-1	2020	The purified active fraction of Albizia julibrissin saponin (AJSAF) is an ideal adjuvant candidate that improves antigen-specific both cellular and humoral immune responses and elicits mixed Th1/Th2 responses, but its mechanisms remain unclear.	Saponins	52-59	negative elongation factor complex member C/D, Th1l	Mus musculus	191-194	
20847539-1	2011	Saponin is the generic name of steroid or triterpene glycosides, and the capacities of some saponins to stimulate both Th1 immune response and production of cytotoxic T cells are useful as vaccine components against intracellular pathogens.	Saponins	92-100	negative elongation factor complex member C/D, Th1l	Mus musculus	119-122	
1457190-4	1992	All the cultures secreted IL-5, but only those from saponin-immunized mice produced IFN gamma, suggesting that saponin is capable of activating both the Th1 and TH2 T-cell subsets.	Saponins	52-59	negative elongation factor complex member C/D, Th1l	Mus musculus	153-156	
1457190-4	1992	All the cultures secreted IL-5, but only those from saponin-immunized mice produced IFN gamma, suggesting that saponin is capable of activating both the Th1 and TH2 T-cell subsets.	Saponins	111-118	negative elongation factor complex member C/D, Th1l	Mus musculus	153-156	
29706292-3	2018	Therefore, the ability of a novel saponin-based adjuvant G3 to inducing balanced Th1 and Th2 responses in BALB/c mice immunized with a split trivalent seasonal influenza vaccine was evaluated in comparison to that of the adjuvant Al(OH)3.	Saponins	34-41	negative elongation factor complex member C/D, Th1l	Mus musculus	81-84	
24754510-0	2014	Immunomodulatory effect of tea saponin in immune T-cells and T-lymphoma cells via regulation of Th1, Th2 immune response and MAPK/ERK2 signaling pathway.	Saponins	31-38	negative elongation factor complex member C/D, Th1l	Mus musculus	96-99	
24754510-9	2014	Th1 cytokines enhancer and Th2 cytokines and NF-kappaB inhibitor, tea saponin can markedly inhibit the proliferation and invasiveness of T-lymphoma (EL4) cells, possibly due to TNF-alpha- and NF-kappaB-mediated regulation of MAPK signaling pathway.	Saponins	70-77	negative elongation factor complex member C/D, Th1l	Mus musculus	0-3