PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24669284-0	2014	Saponins from Aralia taibaiensis attenuate D-galactose-induced aging in rats by activating FOXO3a and Nrf2 pathways.	Saponins	0-8	NFE2 like bZIP transcription factor 2	Rattus norvegicus	102-106	
29849908-6	2018	In aggregate, DKSM and PSRE attenuated the hypercholesterolemia-associated oxidative stress and systemic inflammation in rats, potentially by enhancement of hepatic endogenous antioxidant defense via activation of the Nrf2-ARE pathway, which may be contributed by the rich content of phenolics and saponins in DKSM and PSRE.	Saponins	298-306	NFE2 like bZIP transcription factor 2	Rattus norvegicus	218-222	
24955212-0	2014	Panaxatriol saponins attenuated oxygen-glucose deprivation injury in PC12 cells via activation of PI3K/Akt and Nrf2 signaling pathway.	Saponins	12-20	NFE2 like bZIP transcription factor 2	Rattus norvegicus	111-115	
30209929-6	2016	Compared with aging model rats,total saponins of Panax japonicus increased the expressions of Occludin,ZO-1,Nrf2,HO-1,NQO-1,Sirt1 and PGC-1alpha( P < 0.	Saponins	37-45	NFE2 like bZIP transcription factor 2	Rattus norvegicus	108-112	
24669284-9	2014	By activating FOXO3a and Nrf2 pathways, saponins increase their downstream multiple antioxidants expression and function, at least in part contributing to the protection on the D-galactose-induced aging in rats.	Saponins	40-48	NFE2 like bZIP transcription factor 2	Rattus norvegicus	25-29